“…Some investigators have noted a slight to moderate decrease (Barber et al, 1955;Best et al, 1954;Joyner et al, 1954) and others have found no effect (Friedman et al, 1955;Wilkinson et al, 1955) in the plasma cholesterol after ingestion of sitosterols. It has been suggested (Friedman et al, 1956) that the latter may even initiate atherosclerosis.…”