The self-association of cytoplasmic malate dehydrogenase 1 promotes malate biosynthesis and confers disease resistance in cassava

Zhou, Mengmeng; Wang, Guanqi; Bai, Ruoyu; Zhao, Huiping; Ge, Zhongyuan; Shi, Haitao

doi:10.1016/j.plaphy.2023.107814

Cited by 4 publications

(2 citation statements)

References 40 publications

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“…In cassava, the self-association of MeMDH1 promotes malate biosynthesis and confers disease resistance. The Cys330 residue is directly associated with MeMDH1 self-association and enzyme activity [ 41 ]. Peach exhibits a wide range of homodimer and heterodimer patterns among TIFY members, enabling their significant involvement in various biological processes [ 42 ].…”

Section: Discussionmentioning

confidence: 99%

Genome-wide identification, expression profiling, and protein interaction analysis of the CCoAOMT gene family in the tea plant (Camellia sinensis)

Wang,

et al. 2024

BMC Genomics

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Background The caffeoyl-CoA-O methyltransferase (CCoAOMT) family plays a crucial role in the oxidative methylation of phenolic substances and is involved in various plant processes, including growth, development, and stress response. However, there is a limited understanding of the interactions among CCoAOMT protein members in tea plants. Results In this study, we identified 10 members of the CsCCoAOMT family in the genome of Camellia sinensis (cultivar ‘HuangDan’), characterized by conserved gene structures and motifs. These CsCCoAOMT members were located on six different chromosomes (1, 2, 3, 4, 6, and 14). Based on phylogenetic analysis, CsCCoAOMT can be divided into two groups: I and II. Notably, the CsCCoAOMT members of group Ia are likely to be candidate genes involved in lignin biosynthesis. Moreover, through the yeast two-hybrid (Y2H) assay, we established protein interaction networks for the CsCCoAOMT family, revealing 9 pairs of members with interaction relationships. Conclusions We identified the CCoAOMT gene family in Camellia sinensis and conducted a comprehensive analysis of their classifications, phylogenetic and synteny relationships, gene structures, protein interactions, tissue-specific expression patterns, and responses to various stresses. Our findings shed light on the evolution and composition of CsCCoAOMT. Notably, the observed interaction among CCoAOMT proteins suggests the potential formation of the O-methyltransferase (OMT) complex during the methylation modification process, expanding our understanding of the functional roles of this gene family in diverse biological processes.

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Section: Discussionmentioning

confidence: 99%

Genome-wide identification, expression profiling, and protein interaction analysis of the CCoAOMT gene family in the tea plant (Camellia sinensis)

Wang,

et al. 2024

BMC Genomics

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“…Malate dehydrogenase (MDH) is a critical metabolic enzyme involved in various plant development processes. In cassava (Manihot esculenta), MeMDH1 positively regulates cassava's resistance to Xanthomonas manihotis by modulating the accumulation of SA and the expression of pathogenesis-related protein 1 [38]. Therefore, it is plausible that rice OsATG13a may participate in rice immune processes through interactions with OsRLK170576, OsKEG1, OsANR1, OsPP2A-4, OsVPE1, and OsMDH1.…”

Section: Discussionmentioning

confidence: 99%

Comprehensive Analysis of Autophagy-Related Genes in Rice Immunity against Magnaporthe oryzae

Xie,

Pei,

Liu

et al. 2024

Plants

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Rice blast disease, caused by the fungus Magnaporthe oryzae, is a significant threat to rice production. Resistant cultivars can effectively resist the invasion of M. oryzae. Thus, the identification of disease-resistant genes is of utmost importance for improving rice production. Autophagy, a cellular process that recycles damaged components, plays a vital role in plant growth, development, senescence, stress response, and immunity. To understand the involvement of autophagy-related genes (ATGs) in rice immune response against M. oryzae, we conducted a comprehensive analysis of 37 OsATGs, including bioinformatic analysis, transcriptome analysis, disease resistance analysis, and protein interaction analysis. Bioinformatic analysis revealed that the promoter regions of 33 OsATGs contained cis-acting elements responsive to salicylic acid (SA) or jasmonic acid (JA), two key hormones involved in plant defense responses. Transcriptome data showed that 21 OsATGs were upregulated during M. oryzae infection. Loss-of-function experiments demonstrated that OsATG6c, OsATG8a, OsATG9b, and OsATG13a contribute to rice blast resistance. Additionally, through protein interaction analysis, we identified five proteins that may interact with OsATG13a and potentially contribute to plant immunity. Our study highlights the important role of autophagy in rice immunity and suggests that OsATGs may enhance resistance to rice blast fungus through the involvement of SA, JA, or immune-related proteins. These findings provide valuable insights for future efforts in improving rice production through the identification and utilization of autophagy-related genes.

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Acyl hydrazone derivatives with trifluoromethylpyridine as potential agrochemical for controlling plant diseases

Wang,

Zhang,

Guo

et al. 2024

Pest Management Science

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BACKGROUNDCrops are consistently under siege by a multitude of pathogens. These pathogenic microorganisms, including viruses and bacteria, result in substantial reductions in quality and yield globally by inducing detrimental crop diseases, thus posing a significant challenge to global food security. However, the biological activity sepectrum of commercially available pesticides is limited and the pesticide efficacy is poor, necessitating the urgent development of broad‐spectrum and efficient strategies for crop disease prevention and control.RESULTSThe bioassay results revealed that certain target compounds demonstrated outstanding in vivo antiviral efficacy against cucumber mosaic virus and tobacco mosaic virus. In particular, compound D6 showed remarkable antiviral activity against CMV, significantly higher than that of the control agent ningnanmycin. Mechanism of action studies have shown that compound D6 could enhance the activity of defense enzymes and upregulate the expression of genes related to disease resistance, thereby enhancing the antiviral effects in plants. In addition, these compounds displayed superior inhibitory activity against plant bacterial diseases. For Xoo, compound D10 showed an excellent inhibitory effect that was better than that of the control agent bismerthiazol. Scanning electron microscopy and fluorescence double‐staining experiments revealed that compound D10 effectively inhibited bacterial growth by disrupting the cell membrane.CONCLUSIONA series of trifluoromethyl hydrazone derivatives were designed and synthesized, and it was found that they have control effects on plant viruses and bacterial diseases. In addition, this study revealed the mechanism of action of the active compounds and demonstrated their potential as multifunctional crop protectants. © 2024 Society of Chemical Industry.

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The self-association of cytoplasmic malate dehydrogenase 1 promotes malate biosynthesis and confers disease resistance in cassava

Cited by 4 publications

References 40 publications

Genome-wide identification, expression profiling, and protein interaction analysis of the CCoAOMT gene family in the tea plant (Camellia sinensis)

Genome-wide identification, expression profiling, and protein interaction analysis of the CCoAOMT gene family in the tea plant (Camellia sinensis)

Comprehensive Analysis of Autophagy-Related Genes in Rice Immunity against Magnaporthe oryzae

Acyl hydrazone derivatives with trifluoromethylpyridine as potential agrochemical for controlling plant diseases

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