The Secondary Metabolite Diversity Analysis of Three Mangifera Foetida L. Varieties Based on Liquid Chromatography-Mass Spectrometry (LC-MS)

Abstract

Mangifera foetida L. (Macang) is the type of mangoes that contains the highest levels of mangiferin which has activity of antioxidant, analgesic, anti-drip, anti-inflammatory, antitumor, immunomodulatory and anti-HIV. The potential of Macang as a drug needs to be assessed through phytochemical studies to obtain information on the diversity of Macang secondary metabolite content that is potential to be developed. The purpose of this study was to reveal the diversity of total secondary metabolite compounds contained in Macang with three varieties (Limus, Batu and Manis) using LC-MS analysis. Sampling was carried out use survey method at Remban and Lesung Batu, Kecamatan Rawas Ulu, Kabupaten Musi Rawas Utara, South Sumatra Province. The chromatogram was analyzed using the MassLynx program to obtain the compounds contained in the sample. Names determination of compounds based on Chemspider database and compound classes based on PubChem. The number of metabolite compounds that become characteristic of three Macang varieties in this study was 667 compounds. Limus has a specific compound of 191 compounds, Batu of 162 compounds, and Manis has a specific compound of 202 compounds. The metabolites found in this study are expected to be useful in phytopharmaca and support Macang conservation efforts that rarely found.

Antibacterial Activity of Extracts of Wild Mango (Mangifera spp.), Ruellia tuberosa L and Leucobryum sp. Causes of Gangrene in Patients with Diabetes Mellitus

“…Pengujian pada jenis M. foetida var. Batu memiliki aktivitas antivirus tertinggi (Fitmawati et al, 2019;Fitmawati et al, 2020a;Fitmawati et al, 2020b). Penelitian ini menggunakan dua jenis mangga liar, yaitu: M. sumatrana, dan M. foetida.…”

AUTHENTICATION OF THREE WAX APPLES CULTIVARS (SYZYGIUM SAMARANGENSE (BLUME) MERR. & L.M. PERRY) BASED ON MORPHOLOGICAL CHARACTER AND FRUIT METABOLITE PROFILE

“…Metabolites are bioactive substances that have multiple structures, so that authentication with metabolite profiles can be used as markers to differentiating samples (Doh et al, 2020). Fitmawati et al, (2021) research stated that Mangifera sumatrana and Mangifera laurina are not the same. These findings reveal the significance of metabolite content as a taxonomic marker.…”