The scientific study of herbal wound healing therapies: Current state of play

Krishnan, Preethi

doi:10.1016/j.cacc.2006.02.009

Cited by 48 publications

(31 citation statements)

References 30 publications

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“…In this study, the result of an increased content of collagen in the wounds of irradiated animals are consistent with findings from previous studies 1,5,7,13 indicating the positive effect of laser on fibroplasia.…”

Section: Discussionsupporting

confidence: 93%

“…Healing activity of laser InGaAlP (660nm) in rats 1 Atividade cicatrizante do laser AlGaInP (660nm) em ratos …”

Section: Wound Healingunclassified

“…Changes in wound healing may present a high cost to society, and also decrease the quality of life for millions of people worldwide. However, attention has turned to the investigation of effective therapeutic strategies, and affordable alternatives that might work in this process 1 .…”

Section: Introductionmentioning

confidence: 99%

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Healing activity of laser InGaAlP (660nm) in rats

Tacon¹,

Santos²,

Parente³

et al. 2011

Acta Cir. Bras.

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PuRPOsE: To evaluate the effect the healing activity of diode laser Indium Gallium Aluminum Phosphorus (InGaAlP) ë660nm on healing of surgical wounds in rats.METHOds: Fifty-four female Wistar rats were used, divided into three groups (n=18) and subdivided into three subgroups (n=6) to be studied in 5, 10 and 15 th days after surgical procedures. The wound was induced in the dorsal-cervical using punch. The lesions were irradiated on alternate days with InGaAlP laser, the energy densities of 3J/cm 2 (L3) or 6J/cm 2 (L6). The control group received no irradiation. At 5, 10 and 15 th days after surgery the animals were euthanized and the repair area was removed and histological sections were stained with hematoxylin-eosin and picrossírius. We evaluated macroscopic and histological lesions in the times cited, as well as morphometric analysis of angiogenesis and collagen content. REsuLTs:The wound healing activity InGaAlP laser was evidenced by increased angiogenesis group L3 and L6 in relation to control group (CG) at the 5 th day (p=0.0001) and decreased polymorphonuclear infiltrate and hemorrhage (p=0.045 and p=0.07 respectively) in the groups L3 and L6 in relation to control group (GC). On the 10 and 15 th days was also observed in groups treated with laser L3 and L6 stimulation was pronounced fibroplasia (p=0.0003 and p=0.034 respectively) when compared with the control group (CG). CONCLusION:The InGaAlP laser acted positively on the healing of skin wounds in rats.Keywords: Wound Healing. Laser Therapy, Low Intensity. Rats. REsuMOOBJETIVO: Avaliar a atividade cicatrizante do laser diodo Alumínio Gálio Índio Fósforo (AlGaInP), ë660nm em feridas cutâneas induzida em ratos. MéTOdOs:Foram utilizados 54 ratos Wistar, fêmeas, divididos em três grupos (n=18) e subdivididos em três subgrupos (n=6) animais para serem estudados no 5, 10 e 15° dias após o procedimento cirúrgico. A ferida foi induzida em região dorso-cervical utilizando punch.

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Section: Discussionsupporting

confidence: 93%

“…Healing activity of laser InGaAlP (660nm) in rats 1 Atividade cicatrizante do laser AlGaInP (660nm) em ratos …”

Section: Wound Healingunclassified

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Healing activity of laser InGaAlP (660nm) in rats

Tacon¹,

Santos²,

Parente³

et al. 2011

Acta Cir. Bras.

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“…Herbal wound healing therapies have been discussed by many authors in the literature (for example, Krishnan (62). These therapies often contain mannans although the therapies are not always promoted on that basis.…”

Section: Woundsmentioning

confidence: 99%

Role of Glucomannans in Immunology

Tester¹,

Al‐Ghazzewi²

2017

J Pharm Pharm Sci

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“…In this regard, Aloe (A. ) vera is considered as one of the promising candidate having immunomodulatory effects in different animal models (Krishnan, 2006).…”

Section: Introductionmentioning

confidence: 99%

Aloe vera Polysaccharides as Biological Response Modifiers in Chickens

Khaliq¹,

Akhtar²,

Iqbal³

et al. 2016

IJAB

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In the present study, polysaccharides have been isolated and evaluated as biological response modifiers in chickens. Aloe (A.) vera polysaccharides were administered in chickens for three consecutive days and used for immunological evaluation. Results showed significantly higher (p<0.05) lymphoproliferative response to PHA-P and Con-A in chickens of polysaccharides administered groups as compared to control. Carbon particle clearance assay showed significantly higher clearance index (K) in control group, indicating presence of more carbon particles in blood. Phagocytic index (α) showed significantly higher response in all three polysaccharides administered groups. Significantly higher humoral immune responses [total immunoglobulins (Igs), IgG and IgM titers] were also detected in treatment groups. Biomolecule administered chickens showed better feed conversion ratios and significantly higher (p<0.05) weekly weight gains. From the current study, it was concluded that A. vera derived polysaccharides have potential to be used as immunotherapeutic agent(s) in chickens.

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The scientific study of herbal wound healing therapies: Current state of play

Cited by 48 publications

References 30 publications

Healing activity of laser InGaAlP (660nm) in rats

Healing activity of laser InGaAlP (660nm) in rats

Role of Glucomannans in Immunology

Aloe vera Polysaccharides as Biological Response Modifiers in Chickens

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