2013
DOI: 10.1142/s0218202513400071
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The Scalar Keller–segel Model on Networks

Abstract: In this work, we extend the one-dimensional Keller–Segel model for chemotaxis to general network topologies. We define appropriate coupling conditions ensuring the conservation of mass and show the existence and uniqueness of the solution. For our computational studies, we use a positive preserving first-order scheme satisfying a network CFL condition. Finally, we numerically validate the Keller–Segel network model and present results regarding special network geometries.

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Cited by 37 publications
(42 citation statements)
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“…168 In particular, the specific features of the environment can oblige cells to move along networks rather than a less constrained movement in space homogeneity. 33,128 An additional difficulty is that cells may undergo mutations and selections through a proliferative or destructive dynamics. 63 Therefore, the properties of cells and their number evolve in time in a system, which is not mass conservative.…”
Section: A Micro-macro Approachmentioning
confidence: 99%
“…168 In particular, the specific features of the environment can oblige cells to move along networks rather than a less constrained movement in space homogeneity. 33,128 An additional difficulty is that cells may undergo mutations and selections through a proliferative or destructive dynamics. 63 Therefore, the properties of cells and their number evolve in time in a system, which is not mass conservative.…”
Section: A Micro-macro Approachmentioning
confidence: 99%
“…The FVM, which is referred to as the Dual-Finite Volume Method (DFVM) [1,13], is used for numerically solving (3). Detailed discretization of the DFVM for linear advection-diffusion equations is described in Yoshioka and Unami [1].…”
Section: Finite Volume Methodsmentioning
confidence: 99%
“…Diffusion-type partial differential equations (PDEs) on connected graphs arise as relevant mathematical models for transport phenomena in environmental [1,2], biological [3], and material problems [4,5]. Here a connected graph is defined as an union of 0-D vertices that links 1-D intervals [6].…”
Section: Introductionmentioning
confidence: 99%
“…Results about hyperbolic models on networks can be found in [6,7,23,19,22], with different kinds of transmission conditions; moreover parabolic chemotaxis models on networks were studied in [1,5,17], with continuity conditions at the nodes.…”
Section: Introductionmentioning
confidence: 99%