“…Theme 3, finally, provides an update about the involvement and role of Ca 2+ signals in pathogenesis and pathology. A wide spectrum of diseases is discussed, including breast cancer [25], neurological disorders, such as Alzheimer's disease [26] and Parkinson's disease [27], chemotherapy-induced neuropathy [28], hepatic diseases [29], cardiac diseases [30], polycystic kidney disease [31], pancreatic diseases [32] and auditory diseases [33].…”