The Role of Vitamin D in Thyroid Diseases

Kim, Do-Hee

doi:10.3390/ijms18091949

Cited by 181 publications

(163 citation statements)

References 82 publications

(170 reference statements)

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“…Research data concerning associations between autoimmune thyroid disease (and thyroid cancer) are inconclusive [2]. In our study 25(OH)D levels were not measured longitudinally; therefore, it is difficult to draw conclusions about the association between vitamin D status and thyroid disorders, although hypothyroid study participants had lower calcidiol levels than euthyroid.…”

Section: Discussionmentioning

confidence: 71%

“…Multiple associations have also been made between vitamin D deficiency and deleterious health effects, including autoimmune, cardiovascular, and neoplastic diseases. The role of vitamin D has been investigated also in the context of autoimmune thyroid disorders (AITD) and to a lesser extent thyroid neoplasms [1,2].…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, vitamin D deficiency was stated in up to 90% of Poland's adult population [9]. The effects of vitamin D on the immune system have been suggested as the link between decreased vitamin D levels and AITD [1,2,10]. The aim of the presented study was to assess vitamin D status among patients with thyroid disorders in Poland during summer months.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Vitamin D status including 3-epi-25(OH)D3 among adult patients with thyroid disorders during summer months

Kmieć

Minkiewicz

Rola³

et al. 2018

Endokrynologia Polska

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Section: Discussionmentioning

confidence: 71%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Vitamin D status including 3-epi-25(OH)D3 among adult patients with thyroid disorders during summer months

Kmieć

Minkiewicz

Rola³

et al. 2018

Endokrynologia Polska

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“…In addition, participants with thyroid diseases were included in their study; 23.5% were found to have euthyroid multinodular goiter and 33.8% were with hypothyroidism. These could have influenced their results (61). Furthermore, 17.4% of the non-diabetic Saudi participants were lost to follow-up.…”

Section: Discussionmentioning

confidence: 99%

The prevalence of vitamin D deficiency between Saudis and non-Saudis in Al-Madinah Al-Munawarah a cross-sectional study

Nasr

Othman

Hassan

et al. 2019

Preprint

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BackgroundVitamin D, or the “sunshine” hormone became an attractable topic that recently captivates many researchers. The increased prevalence of vitamin D deficiency became an alarming health concern despite the accumulative evidence exploring its crucial role not only in bone metabolism, but also in a variety of pleiotropic functions throughout the various body organs. The aim of this study is to compare the prevalence that might influence vitamin D deficiency among Saudi and non-Saudi nationalities in Almadinah Almunawarh, Saudi Arabia, and to study the different factors that may have an influence in the difference of this prevalence like the marital status, occupation, smoking, sunlight exposure, education, and dietary habits.MethodsThe study was a cross sectional study done in the medical care unit in Taiba University Almadina Almunawarah in which, 65 healthy male individuals from different nationalities (Saudis and non-Saudis), aged 18 - 65 years were divided into 2 groups, 33 Saudis and 32 non-Saudis. A sociodemographic questionnaire was filled by the study participants and 25-OH vitamin D3 (25(OH)D3) concentrations were detected by electrochemiluminescence immunoassay.ResultsResults showed a Significant percentage of the participants in the Saudi group (n = 30, 91%) suffered from deficiency in vitamin D levels [25 (OH) D < 20 ng/ml] 12.57 ± 4.82 (mean ± SD), compared to only 47% (n = 15) in the non-Saudi group [21.56 ± 6.82 (mean ± SD)]. Vitamin D deficiency was found to be significantly higher in the Saudi group than the non-Saudi group with P = 0.001.ConclusionResults showed a significant increase in vitamin D deficiency in Saudi population than the non-Saudis P = 0.001. The occupation status was found to be the only factor positively correlated with vitamin D deficiency.

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“…Vitamin D deficiency may play an important role in pathogenesis of infections, autoimmune diseases, metabolic syndromes, cardiovascular diseases, cancers and all-cause mortality (1, 2). In recent years there have been many studies published, which showed vitamin D associations with autoimmune thyroid diseas-es, including Hashimoto's thyroiditis (HT), postpartum thyroiditis (PPT) and Graves' disease (GD) (3,4). Vitamin D occurs in two different forms, as cholecalciferol (vitamin D 3 ) and ergocalciferol (vitamin D 2 ).…”

Section: Introductionmentioning

confidence: 99%

Vitamin D and autoimmune thyroid diseases

Kochman¹

2017

PNM

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S u m m a r yVitamin D is one of the most important factors regulating calciuam and phosphorus homeostasis and bone metabolism. In the last years increasing evidences suggest an important role of vitamin D deficiency in many extra-skeletal disorders, such as metabolic syndromes, cardiovascular diseases, cancers, infections and autoimmune disorders, including rheumatoid arthritis, Crohn disease, multiple sclerosis and type 1 diabetes mellitus. Many studies has shown also an association of vitamin D deficiency with occurrence and development of autoimmune thyroid diseases including Hashimoto's thyroiditis, postpartum thyroiditis and Graves' disease. In recent years there are increasing data indicating that vitamin D supplementation may prevent these pathologies or alleviate their course. Some studies suggest also that vitamin D may influence thyroid function. This review presents current data on the relationship of vitamin D and thyroid autoimmunization and function. The effects of vitamin D supplementation on the development and progression of autoimmune thyroid disease have also been discussed. S t r e s z c z e n i e Witamina D jest jednym z głównych czynników regulujących homeostazę wapnia i fosforu oraz metabolizm kostny. W ostatnich latach coraz więcej dowodów wskazuje na ważną rolę niedoboru witaminy D w wielu schorzeniach spoza układu kostnego, takich jak zespoły metaboliczne, choroby układu sercowo-naczyniowego, nowotwory, infekcje oraz zaburzenia autoimmunizacyjne, w tym reumatoidalne zapalenie stawów, choroba Leśniowskiego-Crohna, stwardnienie rozsiane czy cukrzyca typu 1. Wiele badań wykazało także związek między niedoborem witaminy D a chorobami autoimmunizacyjnymi tarczycy, w tym zapaleniem tarczycy Hashimoto, poporodowym zapaleniem tarczycy i chorobą Gravesa-Basedowa. W ostatnich latach coraz więcej danych wskazuje na to, że uzupełnianie niedoboru witaminy D może zapobiegać tym patologiom lub łagodzić ich przebieg. Niektóre badania sugerują także, że witamina D może mieć wpływ na czynność hormonalną gruczołu tarczowego. W artykule przedstawiono najnowsze doniesienia dotyczące związku witaminy D z procesami autoimmunizacyjnymi w tarczycy i jej czynnością hormonalną. Omówiono także wpływ suplementacji witaminą D na rozwój i przebieg autoimmunizacyjnych chorób tarczycy.

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The Role of Vitamin D in Thyroid Diseases

Cited by 181 publications

References 82 publications

Vitamin D status including 3-epi-25(OH)D3 among adult patients with thyroid disorders during summer months

Vitamin D status including 3-epi-25(OH)D3 among adult patients with thyroid disorders during summer months

The prevalence of vitamin D deficiency between Saudis and non-Saudis in Al-Madinah Al-Munawarah a cross-sectional study

Vitamin D and autoimmune thyroid diseases

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