The Role of Trace Elements in Retinal Diseases

Abstract

Background: The role of serum zinc, and magnesium concentration activities in association with the Blood sugar level, and their link as biochemical marker risk for lens damage, inflammation, for the Retinal disease patients with diabetes beside lens replacement surgery, and in control individuals for both genders. Our purpose for the current study is to investigate serum concentration levels of blood sugar, zinc, and magnesium, as trace elements for patients with retinal diseases with diabetes in correlation with healthy subjects, and their effect on eye function, lens damage, inflammation, and bacterial or viral infections, or even undergo artificial intraocular lens surgery. Also to find a diagnostic prediction for blood sugar, magnesemia and zinc levels may induce causing diabetes retinopathy, cataract, or even glaucoma. Materials and methods: Total of forty six diabetic retinopathy patients their mean is (53.36±16.3), and thirty four healthy controls with mean of (49.91±21.72) have been studied. The age has non-significantly (P>0.05) differ in diabetic retinopathy patients (53.36±16.31 year) from normal subjects (49.91±21.72 year). Retinal disease patients are diagnosed on the basis of pathological condition into diabetic retinopathy patients. Results: Assessment, of serum zinc, and magnesium, and blood glucose levels were done for all groups. The concentricity of serum zinc levels are depressed, and non-significantly differ for diabetic retinopathy patients, higher in (33±19.48 ng/L with P= 0.122), from that of normal subjects. Whilst the level of magnesium was exhibited to be decreased for diabetic retinopathy patients, they showed (1.74±0.34 ng/L with P = 0.390) from that of normal subjects. Moreover, blood sugar levels are increased in diabetes than control (10.27±4.62 μmol/L versus 5.23±0.40 μmol/L with P = 0.0001). All parameters has are correlated non-significantly association with each other for diabetic retinopathy patients.