The role of the inferior frontal gyri in cognitive processing of patients with Parkinson's disease: A pilot rTMS study

Abstract

In PD patients, rTMS of the IFG increased the speed of cognitive processing in both the congruent and incongruent conditions of the ST.

Non-invasive brain stimulation of the right inferior frontal gyrus may improve attention in early Alzheimer's disease: A pilot study

“…We report here the preliminary results focused solely on the effects of right IFG stimulation in AD subjects. We previously showed that rTMS applied over the IFG enhanced cognitive speed in a group (n = 10) of non-demented Parkinson's disease (PD) subjects regardless of cognitive load [46]. In the same vein, rTMS applied over the right IFG decreased the latency of P3 waves recorded in the subthalamic nucleus of PD subjects during both simple and dual executive tasks [4].…”

“…[16,25,27,32]). Based on our previous functional magnetic resonance imaging (fMRI) and rTMS results in patients with degenerative brain diseases, we chose two cortical areas to study: the right inferior frontal gyrus (IFG) in order to modulate attention and cognitive speed [4,43,44,46] and the right superior temporal gyrus (STG) in order to manipulate visual processing, visual memory encoding, and recognition [7,27] in AD population. These brain areas are easily accessible by rTMS when the coil is navigated by a frameless stereotaxy.…”

Combining functional imaging with brain stimulation in Parkinson's disease

“…Along the same line, inhibition of familiar responses measured with the Stroop test showed improved performance after 5 Hz rTMS of the left DLPFC (Pal et al, 2010) but not with 10 Hz rTMS, which did not enhance patients ' executive functions (Sedlackova et al, 2009). Recently, 25 Hz rTMS stimulation of the right IFC produced enhanced performance of a Stroop test (Srovnalova et al, 2011). The combination of TMS with imaging techniques has provided relevant information for understanding TMS effects and how clinical benefi ts may take place based on neurotransmitter release or network activation in remote regions from the stimulated area.…”

Relearning of writing skills in Parkinson's disease: A literature review on influential factors and optimal strategies

“…It was shown that anodal tDCS of the left dorsolateral prefrontal cortex resulted in significant improvements in working memory of PD patients (Boggio et al, 2006). In addition, 1 session of 25 Hz-rTMS over the left and right inferior frontal gyri led to an increased speed of cognitive processing in PD patients (Srovnalova et al, 2011).…”