1995
DOI: 10.1006/gyno.1995.1004
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The Role of Serum Tetranectin, CA 125, and a Combined Index as Tumor Markers in Women with Pelvic Tumors

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Cited by 24 publications
(11 citation statements)
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“…For CA125, markedly elevated median levels were found for the malignant patient groups compared to the benign patient group. For TN, the decreased median levels for each patient group corresponded with previous reports, except for localized OC stage IϩII (Høgdall et al, 1991b(Høgdall et al, , 1995. Normal levels of TN found in localized OCs may reflect smaller tumour volumes in the present patients compared to the other reported studies or a better prognosis for the present patients than in the earlier reported studies, where low TN values were significantly correlated with poor prognosis (Høgdall et al, 1993b).…”
Section: Discussionsupporting
confidence: 86%
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“…For CA125, markedly elevated median levels were found for the malignant patient groups compared to the benign patient group. For TN, the decreased median levels for each patient group corresponded with previous reports, except for localized OC stage IϩII (Høgdall et al, 1991b(Høgdall et al, , 1995. Normal levels of TN found in localized OCs may reflect smaller tumour volumes in the present patients compared to the other reported studies or a better prognosis for the present patients than in the earlier reported studies, where low TN values were significantly correlated with poor prognosis (Høgdall et al, 1993b).…”
Section: Discussionsupporting
confidence: 86%
“…In Table III, the generally accepted cut-offs for the different markers are used in the calculations of sensitivity and specificity: TN, 7 mg/l (Høgdall et al, 1995); OVX1, 12.1 U/ml (Woolas et al, 1993); CA125, 35 U/ml (Bast et al, 1983); CASA, 6 U/ml (Ward, 1992). Only CA125 had a sensitivity Ͼ60%, whereas the specificities were acceptable for all markers.…”
Section: Resultsmentioning
confidence: 99%
“…12 Serum levels of CA 125 are reported to be elevated in Ͼ 80% of epithelial OC patients. CA 125 measurement has been reported to be a valuable prognostic marker in various studies of primary OC employing univariate life table analyses, 13,14 but it reportedly loses its independent prognostic value in multivariate analyses when clinical International Federation of Gynecology and Obstetrics (FIGO) stage is included in the model.…”
mentioning
confidence: 99%
“…18 Several investigators have reported that plasma and serum TN concentrations in patients with malignant tumours correlate with disease stage and survival. [19][20][21][22][23][24][25][26] Others found that TN expression in tumour tissue correlated with tumour histological grading. 27 The aim of our study was to evaluate the expression of TN in breast cancer tissue and in adjacent normal breast tissue and to investigate its role as a prognostic marker.…”
mentioning
confidence: 99%