The Role of Nutrition in The Treatment of Chronic Musculoskeletal Diseases

Boros, Szilvia

doi:10.15226/2374-6904/4/3/00161

Cited by 3 publications

(5 citation statements)

References 27 publications

(26 reference statements)

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“…For instance, although it was reported that fat and caloric intake is associated with pain severity in patients with osteoarthritis [50], fat and caloric intake were not associated with pain severity in patients with rheumatoid arthritis [51]. This might be due to different underlying pain generator mechanisms [16]. On the other hand, the primary aim of this review was to show all possible interactions between dietary pattern, components of patients' diet, and chronic musculoskeletal pain.…”

Section: Strengths and Limitationsmentioning

confidence: 96%

“…In general, nutrition is an essential part of musculoskeletal health. It has a supportive effect in bone, as well as in cartilage structure and immune modulation [16]. For instance, endogenous pain-relieving systems in the central nervous system require essential fatty acids such as eicosapentaenoic acids, arachidonic acids, and tryptophan [17,18].…”

Section: Introductionmentioning

confidence: 99%

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Do Nutritional Factors Interact with Chronic Musculoskeletal Pain? A Systematic Review

Elma

Yılmaz

Deliens

et al. 2020

JCM

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Dietary patterns may play an important role in musculoskeletal well-being. However, the link between dietary patterns, the components of patients’ diet, and chronic musculoskeletal pain remains unclear. Therefore, the purpose of this review was to systematically review the literature on the link between dietary patterns, the components of patients’ diet and chronic musculoskeletal pain. This review was conducted following the “Preferred Reporting Items for Systematic reviews and Meta-Analyses” (PRISMA) guidelines and was registered in PROSPERO with the registration number CRD42018110782. PubMed, Web of Science, and Embase online databases were searched. After screening titles and abstracts of 20,316 articles and full texts of 347 articles, 12 eligible articles were included in this review, consisting of nine experimental and three observational studies. Seven out of nine experimental studies reported a pain-relieving effect of dietary changes. Additionally, protein, fat, and sugar intake were found to be associated with pain intensity and pain threshold. In conclusion, plant-based diets might have pain relieving effects on chronic musculoskeletal pain. Patients with chronic rheumatoid arthritis pain can show inadequate intake of calcium, folate, zinc, magnesium, and vitamin B6, whilst patients with fibromyalgia can show a lower intake of carbohydrates, proteins, lipids, vitamin A-E-K, folate, selenium, and zinc. Chronic pain severity also shows a positive relation with fat and sugar intake in osteoarthritis, and pain threshold shows a positive association with protein intake in fibromyalgia.

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Section: Strengths and Limitationsmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Do Nutritional Factors Interact with Chronic Musculoskeletal Pain? A Systematic Review

Elma

Yılmaz

Deliens

et al. 2020

JCM

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“…Thus, identifying the musculoskeletal manifestations associated with COVID‐19 and an early diagnosis would be beneficial to manage the condition at its earliest and this also may ensure immediate recovery. Potassium, phosphorous, zinc, calcium, vitamin D, vitamin C, vitamin B1, B2, B3, B5, and B12, vitamin K2, leucine, omega‐3 fatty acids, phosphatidic acid, folic acid, and creatine are some of the examples of nutraceuticals and dietary supplements that are reported to improve the musculoskeletal health and cognitive functions (Boros, 2013 ; Deane et al, 2017 ; Iolascon et al, 2017 ). All these nutraceuticals and dietary supplements are responsible to prevent osteoarthritis and autoimmune disorders and promote bone formation, regulation of proteins in bone tissue, modulating muscle contraction, collagen synthesis, initiating cell division, and osteoblast activity (Boros, 2013 ).…”

Section: Nutraceuticals and The Management Of Covidmentioning

confidence: 99%

“…Potassium, phosphorous, zinc, calcium, vitamin D, vitamin C, vitamin B1, B2, B3, B5, and B12, vitamin K2, leucine, omega‐3 fatty acids, phosphatidic acid, folic acid, and creatine are some of the examples of nutraceuticals and dietary supplements that are reported to improve the musculoskeletal health and cognitive functions (Boros, 2013 ; Deane et al, 2017 ; Iolascon et al, 2017 ). All these nutraceuticals and dietary supplements are responsible to prevent osteoarthritis and autoimmune disorders and promote bone formation, regulation of proteins in bone tissue, modulating muscle contraction, collagen synthesis, initiating cell division, and osteoblast activity (Boros, 2013 ). Apart from all these evidence published in literature regarding the influence of nutraceuticals in managing musculoskeletal manifestations, it is necessary to have accurate information and education regarding the use of appropriate nutraceuticals.…”

Section: Nutraceuticals and The Management Of Covidmentioning

confidence: 99%

Nutraceuticals and COVID‐19: A mechanistic approach toward attenuating the disease complications

Paudel

Patel

Vishwas

et al. 2022

Journal of Food Biochemistry

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Nutraceuticals have emerged as potential compounds to attenuate the COVID‐19 complications. Precisely, these food additives strengthen the overall COVID treatment and enhance the immunity of a person. Such compounds have been used at a large scale, in almost every household due to their better affordability and easy access. Therefore, current research is focused on developing newer advanced formulations from potential drug candidates including nutraceuticals with desirable properties viz, affordability, ease of availability, ease of administration, stability under room temperature, and potentially longer shelf‐lives. As such, various nutraceutical‐based products such as compounds could be promising agents for effectively managing COVID‐19 symptoms and complications. Most importantly, regular consumption of such nutraceuticals has been shown to boost the immune system and prevent viral infections. Nutraceuticals such as vitamins, amino acids, flavonoids like curcumin, and probiotics have been studied for their role in the prevention of COVID‐19 symptoms such as fever, pain, malaise, and dry cough. In this review, we have critically reviewed the potential of various nutraceutical‐based therapeutics for the management of COVID‐19. We searched the information relevant to our topic from search engines such as PubMed and Scopus using COVID‐19, nutraceuticals, probiotics, and vitamins as a keyword. Any scientific literature published in a language other than English was excluded. Practical applications Nutraceuticals possess both nutritional values and medicinal properties. They can aid in the prevention and treatment of diseases, as well as promote physical health and the immune system, normalizing body functions, and improving longevity. Recently, nutraceuticals such as probiotics, vitamins, polyunsaturated fatty acids, trace minerals, and medicinal plants have attracted considerable attention and are widely regarded as potential alternatives to current therapeutic options for the effective management of various diseases, including COVID‐19.

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“…A systematic review by Elma et al found evidence from seven out of nine experimental studies indicating the pain-relieving effects of a plant-based diet on chronic musculoskeletal pain. The beneficial effects are theorized to be associated with a higher intake of antioxidants and foods with anti-inflammatory and analgesic properties [ 16 , 17 ]. More high-quality clinical trials and studies are needed to assess the validity of these claims.…”

Section: Introductionmentioning

confidence: 99%

The Role of Nutrient Supplementation in the Management of Chronic Pain in Fibromyalgia: A Narrative Review

et al. 2021

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Introduction:The multifaceted clinical presentation of fibromyalgia (FM) supports the modern understanding of the disorder as a more global condition than one simply affecting pain sensation. The main pharmacologic therapies used clinically include anti-epileptics and antidepressants. Conservative treatment options include exercise, myofascial release, psychotherapy, and nutrient supplementation. Methods: Narrative review. Results: Nutrient supplementation is a broadly investigated treatment modality as numerous deficiencies have been linked to FM. Additionally, a proposed link between gut microbiome patterns and chronic pain syndromes has led to studies investigating probiotics as a possible treatment. Despite positive results, much of the current evidence regarding this topic is of poor quality, with variable study designs, limited sample sizes, and lack of control groups. Conclusions: The etiology of FM is complex, and has shown to be multi-factorial with genetics and environmental exposures lending influence into its development. Preliminary results are promising, however, much of the existing evidence regarding diet supplementation is of poor quality. Further, more robust studies are needed to fully elucidate the potential of this alternative therapeutic option.

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The Role of Nutrition in The Treatment of Chronic Musculoskeletal Diseases

Cited by 3 publications

References 27 publications

Do Nutritional Factors Interact with Chronic Musculoskeletal Pain? A Systematic Review

Do Nutritional Factors Interact with Chronic Musculoskeletal Pain? A Systematic Review

Nutraceuticals and COVID‐19: A mechanistic approach toward attenuating the disease complications

The Role of Nutrient Supplementation in the Management of Chronic Pain in Fibromyalgia: A Narrative Review

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