The role of MRI when relapsing polychondritis is suspected but not proven

Fornadley, John A.; Seibert, D. J.; Ostrov, Barbara E.; Warren, W. Stuart

doi:10.1016/0165-5876(94)01068-9

Cited by 20 publications

(6 citation statements)

References 13 publications

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“…Typical findings of chondritis in the airways of children with clinical evidence of obstruction can be demonstrated through magnetic resonance imaging (MRI) T1 exploration with gadolinium‐DTPA. The use of three‐dimensional computerized axial tomography (CAT) scan reconstruction can show areas of obstruction, therefore making unnecessary the use of invasive procedures such as flexible laryngoscopy (16).…”

Section: Discussionmentioning

confidence: 99%

Relapsing Polychondritis: A Pediatric Case

Fustes‐Morales¹,

León-Bojorge²,

Contreras‐Ruiz³

2002

Pediatric Dermatology

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Section: Discussionmentioning

confidence: 99%

Relapsing Polychondritis: A Pediatric Case

Fustes‐Morales¹,

León-Bojorge²,

Contreras‐Ruiz³

2002

Pediatric Dermatology

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“…Ultra-fast MR scanning (MR fluoroscopy) with gradient echo technique can be used for dynamic, real-time imaging of the larynx with the capability of obtaining 32 to 64 images in less than 60 seconds. 22 In 1995, Fornadley et al 23 found MRI to be useful in helping to establish the diagnosis of tracheal relapsing polychondritis. They reported a case of tracheal relapsing polychondritis in a 10year-old that was diagnosed by MRI and direct laryngoscopy.…”

Section: Discussionmentioning

confidence: 99%

A new role for magnetic resonance imaging in the diagnosis of laryngeal relapsing polychondritis

1999

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Background Relapsing polychondritis involving the upper airway is a rare cause of airflow obstruction and hoarseness. The diagnosis of relapsing polychondritis depends on clinical signs, characteristic findings on cartilage biopsy, and response to treatment. Delays in diagnosis and treatment can increase the morbidity and mortality of the disease. Methods We present a case report of primary laryngeal relapsing polychondritis. Results Serologic testing, direct laryngoscopy, and endoscopic biopsy could not establish the diagnosis of relapsing polychondritis. Magnetic resonance imaging (MRI) examination demonstrated findings consistent with the histopathological diagnosis obtained on open biopsy. Follow‐up MRI after treatment showed resolution of the initial findings. Conclusion This case demonstrates the usefulness of MRI in the diagnosis and management of relapsing polychondritis involving the upper airway. © 1999 John Wiley & Sons, Inc. Head Neck 21: 484–489, 1999.

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“…Magnetic resonance imaging on the other hand correlates well with the histopathologic findings of this disease. It is a better modality than computerized tomography in differentiating inflammation from fibrosis [24][25][26]. Whereas inflammation is hyperintense on T2-weighted images with no enhancement on T1 weighted images after the administration of gadolinium, chronic fibrosis is hyperintense on T1 and T2 weighted images and shows minimal enhancement after contrast injection.…”

Section: Diagnosismentioning

confidence: 99%

Larngeal Manifestations of Relapsing Polychondritis

Hamdan¹,

Sarieddine

2013

OJRA

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The incidence of Relapsing Polychondritis is estimated to be 3.5 cases per million with only 600 cases being reported in the world. It can affect any age ranging from 5 to 84 years with predominance in the fourth and fifth decade. Male to female ratio varies from 1:1 to 1:3. It is believed to be an immunologic reaction to collagen Type II which is predominantly presented in the cartilaginous structures of the body and in the eye. The diagnosis is based on the presence of three or more clinical signs, one clinical sign in addition to histological confirmation, or involvement of two or more sites with a favorable response to treatment based on Mc Adam diagnostic criteria. The otolaryngologic manifestations of RP span the ears, nose, larynx and tracheobronchial tree. The symptoms include change in voice quality, respiratory discomfort, stridor, dyspnea, cough, chocking, anterior neck tenderness mainly over the thyroid cartilage and cricoid cartilages, aspiration and difficulty in swallowing. The laryngeal manifestations should be evaluated using high resolution computerized tomography, Magnetic resonance imaging, pulmonary function testing, plain radiography and pulmonary function testing.

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The role of MRI when relapsing polychondritis is suspected but not proven

Cited by 20 publications

References 13 publications

Relapsing Polychondritis: A Pediatric Case

Relapsing Polychondritis: A Pediatric Case

A new role for magnetic resonance imaging in the diagnosis of laryngeal relapsing polychondritis

Larngeal Manifestations of Relapsing Polychondritis

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