The Role of Medications in Causing Dry Eye

Fraunfelder, Frederick T.; Sciubba, James J.; Mathers, William D.

doi:10.1155/2012/285851

Cited by 103 publications

(77 citation statements)

References 38 publications

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“…Por otra parte, los 6 grupos farmacológicos de medicamentos hallados en el estudio parecen relacionarse con la enfermedad, tal como se observa en otros estudios anteriormente publicados (22).…”

Section: Discussionunclassified

Estudio observacional del ojo seco en una farmacia comunitaria

Estévez¹,

Suances²

2015

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RESUMENIntroducción: El síndrome de ojo seco (SOS) afecta a cinco millones de personas en España y a sesenta millones en todo el mundo, acarreando importantes costes y afectando a actividades diversas. Puede ser de tipo acuodeficiente o evaporativo y el diagnóstico se lleva a cabo según la percepción del paciente, seguida de pruebas objetivas. No tiene curación y el tratamiento va siempre enfocado a paliar los síntomas.Objetivos: Conocer la prevalencia del SOS en A Gudiña (Ourense). Además, se determinó en qué grado la falta de adherencia afecta al tratamiento con lágrimas artificiales (LA); así como la asociación entre el SOS y ciertas variables analizadas.Material y métodos: Durante los siete meses de duración del estudio, se seleccionó una muestra final de 51 pacientes de SOS. Los datos se recogieron cumplimentando una hoja de registro diseñada ad hoc.Resultados: La prevalencia de SOS en A Gudiña es relativamente baja (4,3%). La media de edad es de 66 años, afectando mayoritariamente a mujeres. Se detectó una falta de adherencia al tratamiento con LA. Todas las variables analizadas mostraron asociación con la enfermedad.Conclusiones: La prevalencia de síndrome de ojo seco en A Gudiña es ligeramente menor que la encontrada en la literatura. La exclusión de las LA del seguro médico es la causa principal de la falta de adherencia a los tratamientos. De los antecedentes patológicos valorados en este estudio, la cirugía ocular es el que más afecta en el desarrollo del SOS. Observational study of dry eye in community pharmacy ABSTRACTIntroduction: Dry Eye Disease (DED) is a multifactorial symdrom. It affects five million people in Spain and sixty million persons around the world, carrying significant costs and affecting different activities. DED can be aqueous-deficient or evaporative and diagnosis is performed according to the patient's symptoms, followed by objective tests. It is a chronic disease; therefore, treatment is always focused on alleviating symptoms.Objectives: The main purpose of this study was to set DED prevalence in A Gudiña (a municipality in the province of Ourense). Additionally, it was determined to what extent it is affected by the lack of adherence to the treatment with artificial tears (AT) and the association between DED and certain variables analyzed.Materials and methods: During the seven months of the study, a final sample of 51 DED patients was selected. Data were collected by completing a registration form designed ad hoc.Results: DED prevalence in A Gudiña is relatively low (4.25%). The average age being 66, it was proved to affect mostly women. A lack of adherence to the treatment with AT was reported. All variables analyzed showed association with the disease.Conclusions: DED prevalence in A Gudiña is lower than that found in the literature. The exclusion of AT from health insurance is the main cause of low adherence to treatment. From the set of the medical variables analyzed, eye surgery is the main source of DED development. PALABRAS CLAVESíndrome de ojo seco, farmacia comunitari...

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Section: Discussionunclassified

Estudio observacional del ojo seco en una farmacia comunitaria

Estévez¹,

Suances²

2015

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“…A higher incidence of autoimmune diseases (Sjogren syndrome, and rheumatoid arthritis) correlates with aging, as well as a decreased corneal sensitivity, both causing a decrease in tear production [17]. Deficient tear production can also be caused by a chronic use of systemic and topic medications, which in the elderly accumulate over time, especially for those affected by glaucoma [18].…”

Section: Endogenous and Iatrogenic Causes Of Age-related Dry Eyementioning

confidence: 99%

Age-Related Dry Eye Lactoferrin and Lactobionic Acid

Rusciano¹,

Pezzino²,

Olivieri³

et al. 2018

Ophthalmic Res

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Dry eye is the most prominent pathology among those involving the ocular surface: a decrease of the aqueous (less frequent) or the lipid (more frequent) component of the tear film is the cause of the diminished stability of tears that is observed in this pathology. Dry eye shows a clear distribution linked to both sex (being more frequent among women) and age (increasing with aging). Therefore, specific treatments taking into account the etiology of the disease would be desired. The role of lactoferrin and its functional mimetic lactobionic acid are reported here as a possible remedy for age-related dry eye.

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“…Note that rabbit eyes treated with BAK showed decreased corneal sensitivity and doseand time related corneal nerve damage [55]. Fraunfelder et al [55,56] have pointed out that there is good evidence to show that topical BAK may cause dry eye.…”

Section: Cyclosporine Amentioning

confidence: 99%