The role of internal and external stimuli in the rational design of skin-specific drug delivery systems

Yang, Chen; Chen, Naiying; Feng, Xun

doi:10.1016/j.ijpharm.2020.120081

Cited by 18 publications

(8 citation statements)

References 138 publications

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“…Due to its numerous benefits, including its non-invasiveness, high spatial resolution, ability to regulate temperature, convenience, and ease of handling, light is utilized as an external stimulus in a variety of biological applications, including the delivery of drugs (Chen et al, 2021). Systems that use NIR to administer drugs have greater advantages than those that use other stimuli.…”

Section: Nir Light-based Photo-responsive Materialsmentioning

confidence: 99%

Nanotechnology: optimal applications in anti-cancer drug medicine treatment and diagnosis

Al-saidi¹,

Hadi²,

Hadi³

2023

Bio. Jour.

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The scientific field devoted the importance of studying nanotechnology, which characterizes nanoparticles and their multi-purpose functions, especially nanomedicine techniques. The review focused on newer technologies in biomedical applications as a drug vector in cancer treatment. To occupy the center stage on most of the biological vectors of drugs for the treatment of cancer. Practically, chemical treatments have harm as they target cancerous and non-cancerous cells alike, the solubility is almost non-existent, and the inability of chemotherapy to penetrate cancerous cells, which opens the way for this technique with clear prospects for the aforementioned purpose. The ability to selectively deliver nano-drugs to targeted cancer cells in an optimal manner and to avoid non-specific interactions with healthy cells. The current review focuses on ways to improve the size, shape, and properties of nanomaterials that can be exploited in cancer therapy. The successful treatment of nanocarriers for cancer can be designed for the future as nanotherapies.

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Section: Nir Light-based Photo-responsive Materialsmentioning

confidence: 99%

Nanotechnology: optimal applications in anti-cancer drug medicine treatment and diagnosis

Al-saidi¹,

Hadi²,

Hadi³

2023

Bio. Jour.

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“…This feature of self-adhesion of chitosan for medical technology is attractive for sutureless surgery. [40][41][42]…”

Section: Chitin and Chitosanmentioning

confidence: 99%

Polysaccharides for Medical Technology: Properties and Applications

Sukhavattanakul

Pisitsak

Ummartyotin

et al. 2022

Macromolecular Bioscience

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Over the past decade, the use of polysaccharides has gained tremendous attention in the field of medical technology. They have been applied in various sectors such as tissue engineering, drug delivery system, face mask, and bio‐sensing. This review article provides an overview and background of polysaccharides for biomedical uses. Different types of polysaccharides, for example, cellulose and its derivatives, chitin and chitosan, hyaluronic acid, alginate, and pectin are presented. They are fabricated in various forms such as hydrogels, nanoparticles, membranes, and as porous mediums. Successful development and improvement of polysaccharide‐based materials will effectively help users to enhance their quality of personal health, decrease cost, and eventually increase the quality of life with respect to sustainability.

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“…Stimuli-responsive delivery systems are smart approaches for the controlled and sitespecific release of molecules [168]. Siebert et al (2021) proposed a multifunctional wound hydrogel patch containing VEGF decorated with photoactive tetrapodal zinc oxide and activated through ultraviolet/visible light stimulus.…”

Section: Peptides and Proteinsmentioning

confidence: 99%

3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery

et al. 2021

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3D printing has been widely used for the personalization of therapies and on-demand production of complex pharmaceutical forms. Recently, 3D printing has been explored as a tool for the development of topical dosage forms and wound dressings. Thus, this review aims to present advances related to the use of 3D printing for the development of pharmaceutical and biomedical products for topical skin applications, covering plain dressing and products for the delivery of active ingredients to the skin. Based on the data acquired, the important growth in the number of publications over the last years confirms its interest. The semisolid extrusion technique has been the most reported one, probably because it allows the use of a broad range of polymers, creating the most diverse therapeutic approaches. 3D printing has been an excellent field for customizing dressings, according to individual needs. Studies discussed here imply the use of metals, nanoparticles, drugs, natural compounds and proteins and peptides for the treatment of wound healing, acne, pain relief, and anti-wrinkle, among others. The confluence of 3D printing and topical applications has undeniable advantages, and we would like to encourage the research groups to explore this field to improve the patient’s life quality, adherence and treatment efficacy.

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The role of internal and external stimuli in the rational design of skin-specific drug delivery systems

Cited by 18 publications

References 138 publications

Nanotechnology: optimal applications in anti-cancer drug medicine treatment and diagnosis

Nanotechnology: optimal applications in anti-cancer drug medicine treatment and diagnosis

Polysaccharides for Medical Technology: Properties and Applications

3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery

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