The Role of High-Resolution Computed Tomography and Magnetic Resonance Imaging in the Evaluation of Isolated Orbital Neurofibromas

Park, Won Chan; White, William A.; Woog, John J.; Garrity, James A.; Kim, Yoon Duck; Lane, John I.; Witte, Robert J.; Babovic‐Vuksanovic, Dusica

doi:10.1016/j.ajo.2006.04.060

Cited by 18 publications

(3 citation statements)

References 7 publications

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“…5,9,10,12,13 It is our opinion that, compared with enhanced T1-and T2-weighted images, unenhanced T1-weighted images have less value in the differential diagnosis of schwannoma. Some of the features of schwannoma, including a well-circumscribed round or ovoid shape, iso-or hypointensity on T1-weighted imaging, solitary fibrous tumours, 16 isolated neurofibromas, 17 cavernous hemangiomas, 18 and meningiomas, are shared by a number of other orbital lesions. 19 It is difficult to distinguish these lesions from those of schwannoma on T1-weighted images.…”

Section: Eyementioning

confidence: 99%

Orbital schwannomas: findings from magnetic resonance imaging in 62 cases

Wang

Xiao

2007

Eye

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Purpose To evaluate the diagnostic value of magnetic resonance imaging (MRI) and illustrate the common MRI features of orbital schwannoma. Methods We reviewed 62 consecutive cases of pathologically proven orbital schwannoma investigated by MRI. All cases were examined using T1-and T2-weighted images. Enhanced T1-weighted images were obtained after administration of gadopentetate dimeglumine. The images were analysed and compared. Results Cone-shaped lesions were the most frequent (16, 26%), followed by dumbbell-shaped (10, 16%), oval (9, 15%) and round lesions (8, 13%). The most common site was the superior aspect of the orbit (17, 27%), followed by the medial superior (12, 19%) and the orbital apex (12, 19%). On unenhanced T1-weighted images, 53 (85%) lesions showed isointensity or small patches of hypointensity. The patterns of enhancement seen on T1-weighted images correlated with the signal characteristics of unenhanced T2-weighted images. Five patterns emerged in our series. Among these patterns, the most common sign, found in 18 (29%) cases, was peripheral (ring) enhancement on enhanced T1-weighted images, which showed peripheral isointensity with central hyperintensity on T2-weighted images. Lesions with homogeneous or heterogeneous enhancement were seen in 16 (26%) and 26 (42%) cases, respectively. Conclusions MRI is a valuable diagnostic method for orbital schwannoma, particularly when contrast is applied. The locations and shapes of tumours can be seen distinctly. T1-weighted images are relatively nonspecific. T2-weighted and enhanced T1-weighted images provide information about the pathology of tumours. In particular, peripheral enhancement should be considered a target sign of schwannoma.

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Section: Eyementioning

confidence: 99%

Orbital schwannomas: findings from magnetic resonance imaging in 62 cases

Wang

Xiao

2007

Eye

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“…Clinically, it is impossible to distinguish a cavernous haemangioma from these other lesions prior to surgery. The initial diagnosis of our patient was a neurofibroma both by clinical presentation and by neuroradiological interpretation, as neurofibromas may appear pinkish and hypervascular with occurrence anywhere along the course of the trigeminal nerve 6 7…”

Section: Case Reportmentioning

confidence: 90%

“…MRI scans will show a well-defined lesion that is homogeneously hypo- or isointense with respect to extraocular muscles on T1-weighted imaging, and prominent hyperintensity on T2 imaging with intense contrast enhancement. These features are not pathognomonic for cavernous haemangiomas and can also be seen in haemangiopericytomas, schwannomas and neurofibromas 4 6. Clinically, it is impossible to distinguish a cavernous haemangioma from these other lesions prior to surgery.…”

Section: Case Reportmentioning

confidence: 99%