The role of endoscopy in gastroduodenal obstruction and gastroparesis

Fukami, Norio; Anderson, Michelle A.; Khan, Khalid; Harrison, M. Edwyn; Appalaneni, Vasudhara; Ben–Menachem, Tamir; Decker, G. Anton; Fanelli, Robert D.; Fisher, Laurel; Ikenberry, Steven O.; Jain, Rajeev; Jue, Terry L.; Krinsky, Mary Lee; Maple, John T.; Sharaf, Ravi; Dominitz, Jason A.

doi:10.1016/j.gie.2010.12.003

Cited by 95 publications

(54 citation statements)

References 95 publications

(119 reference statements)

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“…[79][80][81][82][83][84] Risk factors for perforation include dilation in the setting of active ulceration 83 and dilation with balloons greater than 15 mm in diameter. 80,82,83,85 Graded dilation with stepwise increase of balloon size has been suggested to help reduce the risk of perforation. 82,86 Adverse events of foreign body retrieval Adverse events attributable to endoscopic removal of foreign bodies are rare, and it can be difficult to determine whether the adverse event was caused by UGI endoscopy or the foreign object itself.…”

Section: Adverse Events Of Ugi Dilationmentioning

confidence: 99%

Adverse events of upper GI endoscopy

Ben–Menachem¹,

Decker²,

Early³

et al. 2012

Gastrointestinal Endoscopy

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170

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Section: Adverse Events Of Ugi Dilationmentioning

confidence: 99%

Adverse events of upper GI endoscopy

Ben–Menachem¹,

Decker²,

Early³

et al. 2012

Gastrointestinal Endoscopy

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302

170

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“…6 To this end, not only may EGD be utilized in children with suspected gastroparesis to ensure an identifiable underlying etiology is not playing a role, but it may be employed in evaluation of children with known gastroparesis who have persistent symptoms despite therapy. 7 Data to support the endoscopic evaluation of persistent upper GI symptoms in children with known gastroparesis are lacking, as the diagnostic yield of EGD in this population has not been studied. Therefore, we sought to determine the diagnostic yield of EGD with gastroparesis as compared to those without gastroparesis in children with similar clinical symptoms.…”

Section: Introductionmentioning

confidence: 99%

Decreased Relative Diagnostic Yield of Esophagogastroduodenoscopy in Children With Gastroparesis

Wong

Shulman

Chiou

et al. 2014

Journal of Clinical Gastroenterology

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Background Esophagogastroduodenoscopy (EGD) and gastric emptying scintigraphy (GES) are commonly performed in the evaluation of children with upper gastrointestinal (GI) symptoms. It has been presumed, but not clarified, that gastroparesis increases the likelihood of identifying abnormalities on EGD. We sought to determine whether the presence of gastroparesis influenced the diagnostic yield of EGD in children. Methods We conducted a retrospective chart review of children who underwent both an EGD and gastric emptying scintigraphy (GES) within 3 months of each other for evaluation of upper GI symptoms (e.g. abdominal pain). Clinical history (symptoms, comorbidities, medications, and surgical procedures), GES results, and EGD histology reports were captured. Results 125 children (46% female) were included, of whom, 70 (56%) had gastroparesis. 33 (26%) children had liquid-meal GES (1.2 ± 1.1 years of age, mean ± SD) and 92 (64%) had solid-meal GES (12.4 ± 3.6 years of age). There was an overall trend toward a decreased frequency of biopsy abnormalities in those with gastroparesis (P=0.09). Those with gastroparesis identified via liquid-meal GES were less likely to have reflux esophagitis on biopsy (P=0.002). Those with gastroparesis identified on solid-meal GES were less likely to have gastritis (P=0.04). Symptoms, comorbidities, or medications were not predictive of GES or EGD results. Conclusions Children with gastroparesis may be less likely to have biopsy abnormalities identified on EGD in comparison to those without gastroparesis. Further prospective, larger, and multicenter studies are needed to validate our findings.

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“…In order to exclude other disorders that may mimick DGP (rumination syndrome, superior mesenteric artery sindrome, cyclic vomiting syndrome and bulimia nervosa), the diagnosis of gastroparesis is closely made based on typical clinical history, exclusion of gastrointestinal obstruction by endoscopy and abdominal ultrasound, and confirmation of delay in gastric emptying 13,16 . DGP can cause a wide variety of symptoms 13,17 .…”

Section: Clinical Manifestations and Diagnosismentioning

confidence: 99%

Diabetic gastroparesis - from diagnosis to gastric electrical stimulation treatment

et al. 2017

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Abstract. The most common known underlying cause of gastroparesis is diabetes mellitus. General symptoms and signs include nausea, vomiting, bloating and early satiety. The diagnosis of diabetic gastroparesis (DGP) is closely made based on clinical history, exclusion of gastrointestinal obstruction by endoscopy and abdominal ultrasound, and confirmation of delay in gastric emptying by gastric emptying scintigraphy. First-line interventions for DGP are dietary modifications and prokinetic-antiemetic therapy. In cases resistant to maximal medical therapy, gastric electrical stimulation is indicated.The aim is to alleviate both the severity and frequency of symptoms, improve gastric emptying, ameliorate patient's nutritional status and to optimize glycemic control.Key words: diabetes mellitus; electrical stimulation therapy; gastroparesis; scintigraphy Sažetak. Šećerna bolest je najučestaliji poznati uzrok gastropareze. Uobičajeni simptomi su mučnina, povraćanje, nadutost i rano postizanje sitosti. Postavljanje dijagnoze dijabetičke gastropareze (DGP) temelji se na kliničkoj prezentaciji bolesti, otklanjanju mogućnosti opstrukcije endoskopskim ili ultrazvučnim pregledom te na potvrdi usporenog pražnjenja želučanog sadržaja uz pomoć nalaza scintigrafije pražnjenja želuca. Prve terapijske odrednice za DGP su dijetoterapija te uvođenje prokinetika i antiemetika u kroničnu terapiju. Električna stimulacija želuca indicirana je u slučajevima rezistentnim na maksimalnu medikamentoznu terapiju. Cilj je ublažiti intenzitet i učestalost simptoma, poboljšati pražnjenje želuca i nutritivni status pacijenta te optimizirati kontrolu glikemije.

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The role of endoscopy in gastroduodenal obstruction and gastroparesis

Cited by 95 publications

References 95 publications

Adverse events of upper GI endoscopy

Adverse events of upper GI endoscopy

Decreased Relative Diagnostic Yield of Esophagogastroduodenoscopy in Children With Gastroparesis

Diabetic gastroparesis - from diagnosis to gastric electrical stimulation treatment

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