The role of copper nanoparticles in an etch-and-rinse adhesive on antimicrobial activity, mechanical properties and the durability of resin-dentine interfaces

Gutiérrez, Mário Felipe; Malaquias, Pâmela; Hass, Viviane; Matos, Thalita de Paris; Lourenço, Lucas Loram; Reis, Alessandra; Loguércio, Alessandro Dourado; Farago, Paulo Vítor

doi:10.1016/j.jdent.2017.04.007

Cited by 46 publications

(17 citation statements)

References 70 publications

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“…Among these, a wide variety of techniques were employed, sterilization through ethylene oxide being the most commonly used [4,10,11,19,[26][27][28][29]33,34,36,37,40,[42][43][44][45][46][47][48][51][52][53][54]56,57,75,77]. Less commonly used sterilization techniques were: autoclave [3,58], gamma radiation [12,16,83], ultraviolet light [78,80,82,88,90], and incubation in 70% ethanol [30,91,92]. Eight studies did not describe the technique used for sterilization.…”

Section: Discussionmentioning

confidence: 99%

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Antibacterial Properties of Nanoparticles in Dental Restorative Materials. A Systematic Review and Meta-Analysis

et al. 2020

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Background and Objectives: Nanotechnology has become a significant area of research focused mainly on increasing the antibacterial and mechanical properties of dental materials. The aim of the present systematic review and meta-analysis was to examine and quantitatively analyze the current evidence for the addition of different nanoparticles into dental restorative materials, to determine whether their incorporation increases the antibacterial/antimicrobial properties of the materials. Materials and Methods: A literature search was performed in the Pubmed, Scopus, and Embase databases, up to December 2018, following PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines for systematic reviews and meta-analyses. Results: A total of 624 papers were identified in the initial search. After screening the texts and applying inclusion criteria, only 11 of these were selected for quantitative analysis. The incorporation of nanoparticles led to a significant increase (p-value < 0.01) in the antibacterial capacity of all the dental materials synthesized in comparison with control materials. Conclusions: The incorporation of nanoparticles into dental restorative materials was a favorable option; the antibacterial activity of nanoparticle-modified dental materials was significantly higher compared with the original unmodified materials, TiO2 nanoparticles providing the greatest benefits. However, the high heterogeneity among the articles reviewed points to the need for further research and the application of standardized research protocols.

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Section: Discussionmentioning

confidence: 99%

“…Only eight of the 82 studies polished the samples before the antibacterial tests. Four of them [3,81,82,88] used the same technique, polishing samples with silicon carbide paper. The four other works employed different techniques.…”

Section: Discussionmentioning

confidence: 99%

Antibacterial Properties of Nanoparticles in Dental Restorative Materials. A Systematic Review and Meta-Analysis

et al. 2020

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“…There are two methodologies to resist dental caries. The first method is incorporating inorganic antibacterial NPs into resin composites and agents to reduce microorganism biofilm with direct contact [7,8,9,10,11,12,13,14,15,16,17]. Composite resins containing 1% silver nanoparticles (AgNPs) or zinc oxide nanoparticles (ZnO NPs) exhibited a better antibacterial activity.…”

Section: Antimicrobial Applications In Dentistrymentioning

confidence: 99%

Application of Antimicrobial Nanoparticles in Dentistry

2019

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Oral cavity incessantly encounters a plethora of microorganisms. Plaque biofilm—a major cause of caries, periodontitis and other dental diseases—is a complex community of bacteria or fungi that causes infection by protecting pathogenic microorganisms from external drug agents and escaping the host defense mechanisms. Antimicrobial nanoparticles are promising because of several advantages such as ultra-small sizes, large surface-area-to-mass ratio and special physical and chemical properties. To better summarize explorations of antimicrobial nanoparticles and provide directions for future studies, we present the following critical review. The keywords “nanoparticle,” “anti-infective or antibacterial or antimicrobial” and “dentistry” were retrieved from Pubmed, Scopus, Embase and Web of Science databases in the last five years. A total of 172 articles met the requirements were included and discussed in this review. The results show that superior antibacterial properties of nanoparticle biomaterials bring broad prospects in the oral field. This review presents the development, applications and underneath mechanisms of antibacterial nanoparticles in dentistry including restorative dentistry, endodontics, implantology, orthodontics, dental prostheses and periodontal field.

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“…The addition of copper NPs up to 0.5 wt% exhibited antimicrobial features towards ER adhesives and stopped the degradation of the adhesive interface with no reduction in the mechanical features of the formulations. 182 Georgy et al examined the dental adhesive composition containing NPs of metals for gaining lengthy bactericidal features by addition of Ag, V, Cu, Fe, Al, and Ta NPs in the dental adhesive, which resulted in its prolonged bacteriostatic and bactericidal impacts versus dental plaque micro-ora. For tantalum NPs, the modications in the concentrations resulting from the deviation in the working mode of the electric discharge dispersion condensing instrument had no effects on the anti-septic features of the resulting product of the dental adhesive.…”

Section: Nano-materials For Restorationmentioning

confidence: 99%