“…Each migration step could be regulated by distinct molecules including the chemokines (Zlotnik and Yoshie, 2000;Thelen, 2001;Razavi et al, 2004). Of them, the CC chemokine receptor CCR3 belongs to family 1 of the G protein-coupled receptors binding and responding to a variety of chemokines and highly expresses on multiple cells (Oliveira and Lukacs, 2003). Constitutive expression of the CCR3 receptor was detected on normal human bronchial epithelial cells, bronchial epithelial cell lines, and A549 human alveolar type II epithelial cells (Stellato et al, 2001;Adachi et al, 2004;Heiman et al, 2005).…”