2017
DOI: 10.24110/0031-403x-2017-96-4-171-179
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The Role of Antimicrobial Peptides and Vitamin Danti-Infection Protection Formation

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Cited by 9 publications
(8 citation statements)
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“…Cooper et al (2016) showed that whole body bone mineral content in infants born to mothers administered cholecalciferol 1000 IU/day was not significantly different from that in infants born to mothers administered placebo [107]. Vitamin D deficiency during pregnancy impairs fetal skeletal formation and leads to reduced fetal bone mass, but also has a certain effect on the child's susceptibility to diseases immediately after birth, since vitamin D affects the synthesis of surfactant and one of its properties is the ability to stimulate the formation of peptides (β2-defensins and cathelicidins) with pronounced bactericidal activity [108][109][110][111][112][113][114][115][116]. In addition, vitamin D can regulate both adaptive and innate immune responses at the fetal-maternal interface [113][114].…”
Section: Postnatal Outcomesmentioning
confidence: 99%
See 1 more Smart Citation
“…Cooper et al (2016) showed that whole body bone mineral content in infants born to mothers administered cholecalciferol 1000 IU/day was not significantly different from that in infants born to mothers administered placebo [107]. Vitamin D deficiency during pregnancy impairs fetal skeletal formation and leads to reduced fetal bone mass, but also has a certain effect on the child's susceptibility to diseases immediately after birth, since vitamin D affects the synthesis of surfactant and one of its properties is the ability to stimulate the formation of peptides (β2-defensins and cathelicidins) with pronounced bactericidal activity [108][109][110][111][112][113][114][115][116]. In addition, vitamin D can regulate both adaptive and innate immune responses at the fetal-maternal interface [113][114].…”
Section: Postnatal Outcomesmentioning
confidence: 99%
“…Vitamin D deficiency during pregnancy impairs fetal skeletal formation and leads to reduced fetal bone mass, but also has a certain effect on the child's susceptibility to diseases immediately after birth, since vitamin D affects the synthesis of surfactant and one of its properties is the ability to stimulate the formation of peptides (β2-defensins and cathelicidins) with pronounced bactericidal activity [108][109][110][111][112][113][114][115][116]. In addition, vitamin D can regulate both adaptive and innate immune responses at the fetal-maternal interface [113][114]. Vitamin D is a neurosteroid that is essential for the division, growth and differentiation of neurons and has a neuroprotective and neurotrophic effect.…”
Section: Postnatal Outcomesmentioning
confidence: 99%
“…Холекальциферол також відповідає за синтез імуноглобулінів, гістонів і специфічних рецепторів [13]. Одним із важливих механізмів протиінфекційної дії вітаміну D є його здатність індукувати утворення в макрофагах, нейтрофі лах і епітеліальних клітинах β дефензинів та кателіцидину, що викликають загибель мікро організмів в аутофагосомах, проявляючи актив ність щодо бактерій, вірусів і грибків [2,5,13].…”
Section: вступunclassified
“…кафедры педиатрии с кур-сом поликлинической педиатрии имени Г. (3) лежит в основе нарушений минерализации костной ткани, манифестирующей на первом году рахитом, а в последующем -снижением минеральной плотно-сти костей, остеопенией и остеомаляцией [12,24].…”
Section: © коллектив авторов 2018unclassified
“…Присутствие более чем в 40 органах и тканях чувствительных к воздействию 1,25(OH) 2 D специфических рецеп-торов, существование паракринных механизмов трансформации кальцидиола в кальцитриол, несо-мненно, подтверждают наличие у витамина D ши-рокого спектра биологических функций [2][3][4].…”
unclassified