The risk for gastric carcinoma after partial gastrectomy

Domellöf, L; Kg, Janunger

doi:10.1016/0002-9610(77)90439-1

Cited by 122 publications

(33 citation statements)

References 12 publications

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“…These figures are in keeping with other reports [5][6][7][8] that, approximately 15 years after resection, there is an increased risk of mucosal malignancy with each subse quent year. Intuitively, this suggests a continuous carci nogenic influence.…”

Section: Discussionsupporting

confidence: 81%

Carcinoma of Gastric Remnant: A Neglected Postgastrectomy Syndrome?

Heerden

Heath

1989

Dig Surg

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Of patients with gastric carcinoma, ± 1 % of cases will occur in patients who have undergone a prior gastrectomy for benign peptic ulcer disease. The interval between the original operation and the development of gastric malignancy is at least two decades. This possibility must constantly be kept in mind in the follow-up of postgastrectomy patients. It should be included in the differential diagnosis of the so-called postgastrectomy syndromes, particularly when long-standing symptomatology undergoes a subtle change. The majority of these malignancies are advanced at the time of diagnosis, with a mean survival of less than a year.

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Section: Discussionsupporting

confidence: 81%

Carcinoma of Gastric Remnant: A Neglected Postgastrectomy Syndrome?

Heerden

Heath

1989

Dig Surg

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“…Most of the clinical local recurrences of gastrointestinal tumors after resection of the primary tumor occur at the operated area of incision or anastomosis. 57,58 Whether fibrosis is accompanied with tumor or not depends on the types of collagen it produces. 59 Tumor-associated fibrosis is characterized by increased collagen Type III content; such fibrotic lesions are mostly in the early immature stage.…”

Section: Medical Devicesmentioning

confidence: 99%

Beyond foreign‐body‐induced carcinogenesis: Impact of reactive oxygen species derived from inflammatory cells in tumorigenic conversion and tumor progression

Okada

2007

Intl Journal of Cancer

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Foreign-body-induced carcinogenesis is a traditional, maybe old, way of understanding cancer development. A number of novel approaches are available today to elucidate cancer development. However, there are things we learn from the old, and thus I bring out some examples of various clinical cases and experimental models of foreign-body-induced tumorigenesis. What is notable is that the foreign bodies themselves are unrelated to each other, whereas commonly underlying in them is to induce inflammatory reaction, especially stromal proliferation, where those exogenous materials are incorporated and undigested. Such foreign-body-induced carcinogenesis is also recognized in the step of tumor progression, the final step of carcinogenesis that tumor cells acquire malignant phenotypes including metastatic properties. And the phenomenon is universally observed in several cell lines of different origins. In this review I would like to show the evidence that tumor development and progression are accelerated inevitably by inflammation caused from foreign bodies, and that reactive oxygen species derived from inflammatory cells are one of the most important genotoxic mediators to accelerate the process. ' 2007 Wiley-Liss, Inc.

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“…European reports have indicated an increased risk of the development of stump carcinoma with time after surgery for benign disease [4][5][6]. Several authors [6,7] have found the incidence of stump carcinoma to be unaffected by the operative procedure. But in large cohorts with long follow-up (more than 20 years after operation), it has been revealed that gastric stump Abstract Gastric stump carcinoma after gastric surgery for benign disease is now widely recognized as a distinct clinical entity.…”

Section: Epidemiological Features Of Stump Carcinomamentioning

confidence: 99%

“…The mucosa in gastric ulcer patients manifests a high degree of atrophic gastritis, in contrast to that in duodenal ulcer patients, and this might account for the earlier development of carcinoma in the gastric ulcer patients [13,18]. In a large cohort, at 20 or more years after surgery, an increased risk of cancer was found in duodenal ulcer patients, as well as in those with gastric ulcer [5,7]. Janunger et al [19] showed that the differences between the remnant mucosa after duodenal and gastric ulcer surgeries vanished after about 20 years.…”

Section: Clinicopathological Features Of Stump Carcinomamentioning

confidence: 99%

Duodenogastric reflux and gastric stump carcinoma

Kondo

2002

Gastric Cancer

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The risk for gastric carcinoma after partial gastrectomy

Cited by 122 publications

References 12 publications

Carcinoma of Gastric Remnant: A Neglected Postgastrectomy Syndrome?

Carcinoma of Gastric Remnant: A Neglected Postgastrectomy Syndrome?

Beyond foreign‐body‐induced carcinogenesis: Impact of reactive oxygen species derived from inflammatory cells in tumorigenic conversion and tumor progression

Duodenogastric reflux and gastric stump carcinoma

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