The Risk Factors of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis Study

Kiani, Faezeh; Naz, Marzieh Saei Ghare; Sayehmiri, Fatemeh; Sayehmiri, Kourosh; Zali, Hakimeh

doi:10.15296/ijwhr.2017.44

Cited by 15 publications

(11 citation statements)

References 37 publications

(40 reference statements)

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“…Similar findings were seen in women with GDM [20,21]. On the other hand, a metaanalysis showed that the history of macrosomia was only 10% (95% CI: 6-13) in woman with GDM in Iran [22], which may be due to increasing mean age of the population, urban sedentary lifestyle and the increasing the number of obese women. It has been predicted that GDM will arise as the most important threat in Iran [23][24][25].…”

Section: Introductionsupporting

confidence: 54%

Gestational diabetes mellitus in association with macrosomia in Iran: a meta-analysis

Tabrizi

Asemi

Lankarani

et al. 2019

J Diabetes Metab Disord

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Purpose This meta-analysis aimed to estimate the association between gestational diabetes mellitus (GDM) and occurrence of macrosomia for the first time among Iranian population. Methods A systematic review was done of national and international databases. Lists of relevant articles were checked to increase sensitivity of the search reference. Also, access to unpublished articles and documents were accessed by negotiation with related individuals and research centers. These published epidemiological studies (cross-sectional, case-control and cohort studies) were used for comparisons to determine whether GDM was associated with macrosomia. Finally, the Mantel-Haenszel method and the fixed and random-effect models based on heterogeneity of the primary studies were used according to pool results and estimate the odds ratio of macrosomia in women with GDM. Results Of 1870 articles, thirty relevant articles were eligible for the current meta-analysis. Our findings showed that 335 of 2524 women with GDM had macrosomia while only 775 of 26,592 women without GDM had macrosomia. Using random-effect model, the pooled odds ratio (OR) relation between GDM and occurrence of macrosomia was estimated as of 5.49 (95% CI: 4.27-7.04). Subgroup analysis showed no difference regarding different study designs and definitions of macrosomia. There was no evidence of publication bias based on the result of Egger's test (β = 0.1, P = 0.70). Conclusions This meta-analysis shows that GDM is directly associated with the risk of macrosomia in the Iranian population. This confirms the findings of previous studies in the wider scientific literature.

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Section: Introductionsupporting

confidence: 54%

Gestational diabetes mellitus in association with macrosomia in Iran: a meta-analysis

Tabrizi

Asemi

Lankarani

et al. 2019

J Diabetes Metab Disord

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“…coming years and controlling the risk factors can reduce the incidence of diabetes in pregnancy28 .In this present study, 74 cases are delivered and 26 cases are carrying. Out of 74 cases the mode of delivery are assign to be 85.8% patients with caesarean, 12.3% patients with assisted vaginal deliveries and 1.45% patients with normal vaginal deliveries and 5.7% patients meet up with abortion.…”

mentioning

confidence: 79%

THE Drug utilization pattern of gestational diabetes mellitus in pregnant women and complication of gestational diabetes mellitus in mother and newborn in a secondary care hospital: A retrospective study

Ganesan

Raju

Abhraham

2019

J. Drug Delivery Ther.

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The present study was a retrospective study, carried out by total of 100 cases in the Obstetric And Gynaecology department of a secondary care hospital, Tiruppur, Tamil Nadu. There were 100 pregnant women who had gestational diabetes. Increasing gravida (secondary gravida G2 -44% ) shows more prevalence of GDM than primi (34%).Body Mass Index , family history of diabetes and previous history of GDM shows more significance in occurring GDM. Among 100 population, 45% patients receiving insulin with medical nutritional therapy (MNT) ,30% patients receiving medical nutritional therapy (MNT) alone , 11% patients receiving medical nutritional therapy (MNT) with metformin, 3% patients receiving medical nutritional therapy (MNT) with Oral Hypoglycaemic Agents (OHA) and insulin , 3% patients receiving insulin alone and 8% patients didn’t receiving any therapy. Overall 96% of women with GDM had one or more complications and 4% had no complication. From this , 35.89% patients shows caesarean delivery with recurrent GDM, followed by 10.25% patients shows caesarean delivery with polyhydramnios, 15.38% patients shows caesarean delivery with Pregnancy Induced Hypertension (PIH).Overall 74% of new-borns had one or more complications and 27% had no complication. 24.32% patients shows macrosomia with neonatal hypoglycaemia, 16.21% patients shows macrosomia with preterm birth, 13.52% patients shows macrosomia with hyperbilirubinemia. Our study concludes that the complications arise from GDM to both mother and new-borns can be resolved and minimised by proper diagnosis and appropriate treatment during the pregnancy. Keywords: Gestational Diabetes Mellitus, Drug Utilization Pattern, Complications, Oral Glucose Tolerence Test

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“…In agreement with previous studies conducted, family history of diabetes mellitus was signi cantly associated with GDM. Family history of diabetes in rst degree relatives have been found to be the most signi cant risk factors for gestational diabetes which further emphasizes the role of genetics in susceptibility toward this condition [1,6,24,25]. In addition, a study proposed that screening and early identi cation of this possible risk factor in pregnant women would be helpful and cost-effective in planning maternal health services and providing high quality prenatal care to women who may develop gestational diabetes mellitus [26].…”

Section: Discussionmentioning

confidence: 99%

Factors Associated With Gestational Diabetes Mellitus in Rural Areas of Limpopo Province: A Descriptive Analysis

Ntshauba

Maimela

Ntuli

2020

Preprint

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Background: Sustainable Developmental Goal (SDG) no 3 of the United Nations Organisation places emphasise on ensuring healthy lives and promoting the well-being of all people of all age groups. Yet the prevalence of Gestational Diabetes Mellitus (GDM) is increasing and this can have an adverse impact on maternal and infant health and well-being. Currently, more studies have been conducted in International countries on prevalence and risk factors of GDM and few in South African Context. The current study sought to investigate the prevalence, risk factors, maternal and infant outcomes of women with gestational diabetes mellitus in Mopani District. Methods: A cross-sectional descriptive study was conducted amongst pregnant women during Antenatal Care Clinic Visits at Nkhensani Hospital, Nkhensani Gateway clinic and Giyani Healthcare Centre. Information from participants was collected using adapted questionnaire from Michigan Diabetes Research and Training Centre DCP 2.0 and data entry form, captured on Microsoft excel spread sheet and analysed using Statistical Package for Social Sciences (SPSS) and p-value of <0.05 was considered statistically significant.Results: One hundred and one (101) pregnant women (74%) who were attending antenatal care clinic visits at Nkhensani Hospital, Nkhensani Gateway Clinic and Giyani Healthcare Centre completed the questionnaire. Prevalence of Gestational Diabetes Mellitus (GDM) in Mopani District was 1.9% (2 women). Pregnant women above 30 years with secondary education, employed, obese and at gestational age of 31-35 weeks were more likely to present with GDM. A family history of diabetes was significantly associated with development of GDM. Conclusions: The use of various GDM screening strategies across population and countries resulted in discrepancies in the prevalence rate. Universal GDM screening strategy which will benefit our socioeconomic and clinical context to ensure that the true burden of GDM is determined needs to be adopted.

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The Risk Factors of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis Study

Cited by 15 publications

References 37 publications

Gestational diabetes mellitus in association with macrosomia in Iran: a meta-analysis

Gestational diabetes mellitus in association with macrosomia in Iran: a meta-analysis

THE Drug utilization pattern of gestational diabetes mellitus in pregnant women and complication of gestational diabetes mellitus in mother and newborn in a secondary care hospital: A retrospective study

Factors Associated With Gestational Diabetes Mellitus in Rural Areas of Limpopo Province: A Descriptive Analysis

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