The Results of Long-Term Study of Herpesvirus Infection at the Department of Infectious Diseases in Children of Russian National Research Medical University

Шамшева, О. В.; Харламова, Ф С; Егорова, Н. Ю.; Молочкова, О. В.; Новосад, Е. В.; Simonova, Ekaterina; Lebedeva, T. M.; Гусева, Н А

doi:10.22627/2072-8107-2017-16-2-5-12

Cited by 15 publications

(9 citation statements)

References 4 publications

(9 reference statements)

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“…However, many scientists have recently noted its significant changes [6,7,12]. Some authors attribute this to negative ecological state in many countries and the world as a whole, which contributes, firstly, to the change of the virus itself, and secondly, to the formation of immunesuppressive status in contemporary children [1,18,15]. Other researchers believe that changes in the clinical symptoms of rotavirus infection (RVI) are due to the additional infection of the child population, in particular, herpes viruses [10,13,19] At the same time, there are very few studies on clinical and immunological features of RVI in children infected with the herpes group in the available literature, and their results are very contradictory [8].…”

Section: Introductionmentioning

confidence: 99%

Features of the Clinical Course of Rotavirus Infection in Children Infected With Herpes Viruses and Their Blood Interleukin Reactions

Sliepchenko¹

2019

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Background. The widespread prevalence of intestinal infections of rotavirus etiology, the economic damage caused by it and the difficulties of treating patients cause the medical and social significance of this pathology. Along with this, a herpes virus infection and its negative effect on the immune response of the human body is a pressing problem. The purpose of the study is to identify the characteristics of presentation and the course of rotavirus infection in children infected with herpes viruses, and to establish the characteristics of the reaction of interleukins in their blood. Subjects and Methods. 38 children aged one to three years with moderate and severe forms of intestinal infection rotavirus etiology, who received appropriate treatment were examined. The children were divided into two groups: Group 1 included 18 children who did not have a background infection and Group 2 comprised 20 patients with acute rotavirus infection who were infected with herpes viruses. Along with the generally accepted clinical and laboratory examination, the levels of interleukins 1, 4, TNF in the blood serum in the time course of the disease were determined by an ELISA method for all children. Results. Assessment of clinical and immunological parameters of rotavirus infection in children showed that infection with viruses of the herpes group contributed to a less severity of symptoms of the disease at the initial stage, but longer persistence, which was probably due to insufficient reaction of proinflammatory interleukins in blood in the acute period at relatively high levels during the course of the disease.

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Section: Introductionmentioning

confidence: 99%

Features of the Clinical Course of Rotavirus Infection in Children Infected With Herpes Viruses and Their Blood Interleukin Reactions

Sliepchenko¹

2019

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“…Jarrett описал вирус герпеса человека 6-го типа -ВГЧ-6) позволило установить их участие в этиологии инфекционного мононуклеоза. Ряд исследователей сообщают об этиологическом значении вирусов гриппа, аденовирусов [4][5][6][7], токсоплазмы гонди, вирусов гепатита А, В и С, микоплазмы, хламидии, но все сходятся во мнении, что наибольший удельный вес в этиологии инфекционного мононуклеоза составляют все же ВЭБ и другие герпесвирусы [7][8][9][10][11][12][13][14]. Это нашло отражение в Международной классификации болезней десятого пересмотра (МКБ-10).…”

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Clinical manifestations of infectious mononucleosis in primary or reactivated herpes virus infection

Демина

Чеботарева

Мазанкова

et al. 2020

Ross. vestn. perinatol. pediatr.

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Based on the analysis of foreign and domestic literature, the article presents the features of infectious mononucleosis caused by the main pathogens from the Herpesviridae family, course of the disease at various phases of the infectious process. The article identifies clinical and laboratory manifestations characteristic of each pathogen. The authors discuss the issues related to the lack of the unified terminology for describing chronic herpes virus infection. The article discusses the causes of persistent herpes virus infections, risk factors for the adverse course and outcome of herpes virus infections.

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“…Клиника одинакова у всех. Хотя некоторые авторы отмечают, что она может зависеть от возраста больного или этиологии [28,29]. Инкубационный период составляет от 2 до 4 недель.…”

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Infectious Exanthema in Children

Утенкова

2018

Det. infekc.

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The Results of Long-Term Study of Herpesvirus Infection at the Department of Infectious Diseases in Children of Russian National Research Medical University

Cited by 15 publications

References 4 publications

Features of the Clinical Course of Rotavirus Infection in Children Infected With Herpes Viruses and Their Blood Interleukin Reactions

Features of the Clinical Course of Rotavirus Infection in Children Infected With Herpes Viruses and Their Blood Interleukin Reactions

Clinical manifestations of infectious mononucleosis in primary or reactivated herpes virus infection

Infectious Exanthema in Children

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