The response of phimosis to local steroid application

Kikiros, Colin; Beasley, S. W.; Woodward, Ann

doi:10.1007/bf00173357

Cited by 92 publications

(111 citation statements)

References 12 publications

Supporting

Mentioning

103

Contrasting

Unclassified

Order By: Relevance

“…Patients were recruited from the pediatric ward or were referred to us by other physicians. Two urologists independently evaluated the phimosis by gently cleaning and retracting the prepuce to identify the grade of the phimotic ring [11]. …”

Section: Methodsmentioning

confidence: 99%

Incidence of Balanitis Xerotica Obliterans in Boys Younger than 10 Years Presenting with Phimosis

Miernik

Weibl

et al. 2012

Urol Int

View full text Add to dashboard Cite

Objective: Evaluation of the true incidence of balanitis xerotica obliterans (BXO) among boys younger than 10 years. Methods: In a period of 13 months, 75 boys younger than 10 years were treated for phimosis. Suspicion of BXO was raised in phimosis grade 2 or 3 (classification by Kikiros). Patients were offered primarily either circumcision or conservative therapy and circumcision secondarily (if treatment failed in the conservative group). Each circumcision specimen was examined histopathologically. Results: Circumcision was primarily performed in 29 and secondarily in 17 patients. The mean age was 3.7 years (range 1-10). BXO, chronic inflammation, and normal histological results were found in 8/26/12 (17.4/56.5/26.1%) cases, respectively. The mean follow-up was 8.1 months. No recurrences were reported. Conclusions: The incidence of BXO appears to be higher than previously reported. The clinical appearance in children may be confusing. The preoperative BXO suspicion did not correlate with the final histopathological results.

show abstract

Section: Methodsmentioning

confidence: 99%

Incidence of Balanitis Xerotica Obliterans in Boys Younger than 10 Years Presenting with Phimosis

Miernik

Weibl

et al. 2012

Urol Int

View full text Add to dashboard Cite

show abstract

“…Their anti-inflammatory, immunosuppressive, and skin-thinning properties are believed to be the mechanism for resolution of phimosis. 17 Their use in physiological phimosis was first described by Kikiros et al 18 Subsequent studies showed the response rate for resolution of phimosis to be 68.2% to 95%. 16,[19][20][21][22] Moreno et al 23 subsequently performed a meta-analysis and reviewed 12 randomised controlled trials on the use of different topical steroid formulations, and again confirmed the significant benefit of corticosteroids in the complete or partial clinical resolution of phimosis (risk ratio=2.45; 95% confidence interval, 1.84-3.26).…”

Section: Topical Steroidsmentioning

confidence: 99%

Common urological problems in children: prepuce, phimosis, and buried penis

Chan

Wong

2016

Hong Kong Med J

View full text Add to dashboard Cite

“…In a pioneer study on the application of topical corticosteroid in boys with phimosis who were candidates for circumcision, clinical treatment was shown to be viable and efficacious (3). Topical treatment of phimosis with corticosteroids has characteristics that make it quite attractive as the first approach to the treatment of phimosis.…”

Section: Commentsmentioning

confidence: 99%

To circ or not to circ: clinical and pharmacoeconomic outcomes of a prospective trial of topical steroid versus primary circumcision

et al. 2010

View full text Add to dashboard Cite

Purpose: To compare the efficacy and costs of circumcision versus topical treatment using a prospective pharmacoeconomic protocol. Materials and Methods:We treated 59 patients (3-10 years of age) randomized into two groups: 29 underwent an 8-week course of topical treatment with 0.2% betamethasone-hyaluronidase cream twice a day; and 30 underwent circumcision. Topical treatment success was defined as complete exposure of the glans. In cases of treatment failure, circumcision was performed and its cost imputed to that of the initial treatment. The pharmacoeconomic aspects were defined according to the Brazilian National Public Health System database and the Brazilian Community Pharmacies Index. Results: The two groups were statistically similar for all clinical parameters evaluated. Topical treatment resulted in complete exposure of the glans in 52% of the patients. Topical treatment was associated with preputial pain and hyperemia. However, treatment suspension was unnecessary. Minor complications were observed in 16.6% of the surgical group patients. The mean cost per patient was US$ 53.70 and US$ 125.20, respectively, for topical steroid treatment (including the costs related to treatment failure) and circumcision. The total costs were US$ 2,825.32 and US$ 3,885.73 for topical treatment and circumcision, respectively. Conclusions: Topical treatment of phimosis can reduce costs by 27.3% in comparison with circumcision. Therefore, topical treatment of phimosis should be considered prior to the decision to perform surgery.

show abstract

The response of phimosis to local steroid application

Cited by 92 publications

References 12 publications

Incidence of Balanitis Xerotica Obliterans in Boys Younger than 10 Years Presenting with Phimosis

Incidence of Balanitis Xerotica Obliterans in Boys Younger than 10 Years Presenting with Phimosis

Common urological problems in children: prepuce, phimosis, and buried penis

To circ or not to circ: clinical and pharmacoeconomic outcomes of a prospective trial of topical steroid versus primary circumcision

Contact Info

Product

Resources

About