The response of meat ducks from 15 to 35 d of age to gossypol from cottonseed meal

Abstract

The objective of this study was to investigate the responses of meat ducks of 15 to 35 d of age to free gossypol (FG) from cottonseed meal (CSM) and to establish the maximum limits of dietary FG concentration based on growth performance, blood parameters, and tissue residues of gossypol. Nine hundred 15-d-old ducks were randomly allocated to 5 treatments with 10 cages/treatment and 18 ducks/cage on the basis of BW. Five isonitrogenous and isocaloric experimental diets were formulated on a digestible amino acid basis to produce diets in which 0% (without FG), 25% (36 mg FG/kg), 50% (75 mg FG/kg), 75% (111 mg FG/kg), and 100% (153 mg FG/kg) of protein from soybean meal were replaced by that from CSM. Increasing dietary FG content, BW, and ADG decreased (linearly, P < 0.05, except for ADG of days 29 to 35), and F/G linearly increased (P < 0.05). At 35 d, blood hemoglobin, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration linearly decreased (P < 0.05), while serum total protein, albumin, and globulin content linearly decreased (P < 0.05), and the residue of gossypol in liver, kidney, heart, breast, and leg muscle linearly increased (P < 0.001) with increases in dietary FG concentration. Ducks fed 36 mg FG/kg (5.83% CSM of diet) diet had a normal histological structure of liver, and muscle (breast and leg) had no residue of gossypol. The maximum limit of dietary FG concentration was estimated to range from a low of 36 mg/kg to maximize serum globulin concentration to a high of 124 mg/kg to minimize feed intake for 22 to 28d on the basis of a quadratic broken-line model.

Haematological indicators in hybrid mallard ducks (Anas platyrhynchos) with regard to the use of meal from whole white lupin seeds in their diet

“…Zeng et al (2015) assessed the effect of using cottonseed meal as a replacement of soybean meal in the diet of meat type ducks. These authors found that various proportions of cottonseed meal replacement in the diet did not have an effect on the values of the RBC, which is in accordance with the findings in our study, where meal from whole white lupin seeds was used to replace soybean meal.…”

Response of northern bobwhites fed single doses of gossypol

“…Gossypol occurs in both a free and bound form (Zeng et al ). Free gossypol is the active form that readily causes toxic effects in vertebrates.…”

Effect of dietary cotton stalk on nitrogen and free gossypol metabolism in sheep

“…Free gossypol might accumulate in animal tissues over time and have a negative impact on growth performance. Free gossypol toxicity is associated with alterations in blood parameters [15,16]. Gossypol may combine with iron, inhibit the synthesis of respiratory enzymes, and generate excessive reactive oxygen species in the mitochondria [17].…”