The Response of Different Photometers to the Color Produced by Vitamin A and Carotene with Antimony Trichloride

Mj, Caldwell; Db, Parrish; Wg, Schrenk

doi:10.2307/3625859

Cited by 5 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In order to characterize the portable spectrophotometers for quantification of vitamin A, preliminary testing with reference standard oil samples of known vitamin A concentrations can be tested to determine the calibration curve, detection range, and optimal sample and reagent volumes per test. It has been previously reported 29 that the intensity of the blue color developed upon mixing vitamin A and SbCl 3 reagent is unstable and is affected by intensity of the illumination source (LED light) applied during the measurement proces. The optimal intensity of the LED light source and the optimal time instant at which measurement is to be made can be determined by investigating the kinetics of the Carr–Price reaction with the portable spectrophotometer.…”

Section: Design and Development Of A Portable Spectrophotometer For Q...mentioning

confidence: 99%

Portable Devices for Measurement of Vitamin A Concentrations in Edible Oil: Field Readiness of Available Options

et al. 2022

View full text Add to dashboard Cite

Vitamin A (VA) deficiency continues to be a major global health issue, despite measures to increase VA intake via consumption of staple foods such as edible oil. Portable quantitative and semiquantitative devices or test kits for internal quality control have the potential to overcome some of the limitations of traditional methods of testing, such as centralized laboratory, expensive equipment, and specially trained staff. This landscape analysis and comprehensive systematic mini-review catalogs and summarizes evidence on the analytical performance of portable quantitative and semiquantitative devices and test kits for the analysis of VA in edible oil. Studies or reports detailing the usability and validation of portable devices and/or test kits, as well as studies comparing device/test kit performance to a reference standard such as high-performance liquid chromatography (HPLC), were included. Identified devices and test kits were compared for performance versus the reference standard, usability, availability, and other characteristics. We identified four portable methods: two devices, the iCheck CHROMA and iCheck Chroma 3 from BioAnalyt; and two test kits, the QuickView from Bagco Enterprises and the Strategic Alliance for the Fortification of Vegetable Oils (SAFO) Test Kit by Badische Anilin and Soda Fabrik (BASF). Included studies reported the following: an internal validation of the portable method, a comparison of the portable method against a reference standard, a comparison of the portable method against another portable method, and several videos and company websites, which detailed device characteristics. iCheck CHROMA and QuickView quantified VA concentrations with high accuracy and precision compared to the reference standard for field-based quantification, were user-friendly, and provided results within 5 min. iCheck Chroma 3 requires more robust validation against a reference standard. We did not find data on internal validation or comparison against a reference standard for the current version of the SAFO test. Compared to QuickView and SAFO, the iCheck devices can transfer results to a hard drive or the Web, have an online order form for purchase, and meet a minimal set of criteria for point-of-need devices. iCheck, QuickView, and SAFO can quantify VA concentrations in the edible oils tested and determine whether a fortified oil meets country standards. Additional research is needed to validate these devices and test kits across additional oil types and document the ability to meet the minimal criteria for point-of-need devices suggested in this mini-review. Validation against a reference standard is required for SAFO. The limited number of portable methods available may be due to market saturation. Future market and use case analyses to inform the market size and utility of the different tests with publicly available data will allow new manufacturers, particularly those in lower-to-middle-income countries, to enter the market.

show abstract

Section: Design and Development Of A Portable Spectrophotometer For Q...mentioning

confidence: 99%

Portable Devices for Measurement of Vitamin A Concentrations in Edible Oil: Field Readiness of Available Options

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Although certain carotenoids give a blue color with an timony trichloride, Caldwell and Hughes (20) demonstrated that vitamin A possesses chromogenic powers 10-to 25-fold greater than the common carotenoids* In the meastirement of vitamin A in the presence of carotenoids, an appropriate correction majr be made by determining the contribution of the carotene blue color to the total blue color measured at 620 (3,44,144). The necessity for the calibration of each photometer for the determination of vitamin A, as well as the correction factor for the presence of carotenoids has been adequately discussed by Caldwell, Farrish and Shrenk (23).…”

Section: -mentioning

confidence: 99%

Chemistry of glycerol dichlorohydrin as a reagent for the determination of vitamin A

Allen¹

View full text Add to dashboard Cite

Effect of Temperature on Fading of the Carrprice Colors of Vitamin a and Common Carotenoid Pigments

Caldwell¹,

Hughes²

1947

Journal of Biological Chemistry

View full text Add to dashboard Cite

The Response of Different Photometers to the Color Produced by Vitamin A and Carotene with Antimony Trichloride

Cited by 5 publications

References 0 publications

Portable Devices for Measurement of Vitamin A Concentrations in Edible Oil: Field Readiness of Available Options

Portable Devices for Measurement of Vitamin A Concentrations in Edible Oil: Field Readiness of Available Options

Chemistry of glycerol dichlorohydrin as a reagent for the determination of vitamin A

Effect of Temperature on Fading of the Carrprice Colors of Vitamin a and Common Carotenoid Pigments

Contact Info

Product

Resources

About