The Respiratory Dead Space

Rossier, Paul; Bühlmann, A

doi:10.1152/physrev.1955.35.4.860

Cited by 46 publications

(14 citation statements)

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“…Associated with this increased tidal volume the respiratory physiological dead space as measured by the CO2 method and using the Bohr formula is increased while the dead space/tidal volume fraction is reduced (9). This response with values which were similar to those in the literature were found for the individuals of the normal control group and those of Group I (lumbar lesions).…”

Section: Discussionsupporting

confidence: 81%

“…If 4.75. The problem of measuring respiratory dead space by the CO2 method is one on which some of the most heated controversies of exercise physiology have been waged and many of the problems are still unsettled (9). It is concluded from the observations here reported that with diaphragmatic breathing of cervical paraplegics, physiological dead space does not increase but may decrease with exercise.…”

Section: Discussionmentioning

confidence: 69%

“…It was found that with the normal control group and Group I (lumbar lesion) and II (thoracic lesion) the ex-piratory reserve volume percentage of the vital capacity was approximately the same, i.e., approximately 17 to 19 per cent. With Group III (cervical lesions) the expiratory reserve volume was approximately 9 per cent of the vital capacity, a reduction from the normal value of approximately one-half. The surprising finding is that these patients with no functional expiratory muscles can exhale forcibly this much air from the resting expiratory level.…”

Section: Discussionmentioning

confidence: 85%

See 2 more Smart Citations

An Investigation of the Pulmonary Function of Paraplegics1

Hemingway¹,

Bors²,

Hobby³

1958

J. Clin. Invest.

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Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 85%

See 1 more Smart Citation

An Investigation of the Pulmonary Function of Paraplegics1

Hemingway¹,

Bors²,

Hobby³

1958

J. Clin. Invest.

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“…However, this contention could reasonably be rejected either because recruited alveoli were diseased, or because increased VT did not effectively recruit new lung areas. In the case of VD,Bohr/VT or Effc, their change with VT can be explained by some degree of amplitude dependence of those indices [14,24,25], but does not necessarily imply a true improvement in alveolar ventilatory distribution.…”

Section: Discussionmentioning

confidence: 99%

“…2) The classical Bohr estimation of alveolar dead space was calculated according to the equation [14,15]:…”

Section: Calculation Of Capnographic Indices On the Peco 2 (V) Curvementioning

confidence: 99%

Physiologically based indices of volumetric capnography in patients receiving mechanical ventilation

Romero

Lucangelo²,

Aguilar³

et al. 1997

Eur Respir J

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Several indices of ventilatory heterogeneity can be identified from the expiratory CO 2 partial pressure or CO 2 elimination versus volume curves. The aims of this study were: 1) to analyse several computerizable indices of volumetric capnography in order to detect ventilatory disturbances; and 2) to establish the relationship between those indices and respiratory system mechanics in subjects with normal lungs and in patients with acute respiratory distress syndrome (ARDS), both receiving mechanical ventilation.We studied six normal subjects and five patients with early ARDS mechanically ventilated at three levels of tidal volume (VT). Respiratory system mechanics were assessed by end-expiratory and end-inspiratory occlusion methods, respectively. We determined Phase III slopes, Fletcher's efficiency index, Bohr's dead space (VD,Bohr/VT), and the ratio of alveolar ejection volume to tidal volume (VAE/VT) from expiratory capnograms, as a function of expired volume.Differences between normal subjects and ARDS patients were significant both for capnographic and mechanical parameters. Changes in VT significantly altered capnographic indices in normal subjects, but failed to change ventilatory mechanics and VAE/VT in ARDS patients. After adjusting for breathing pattern, VAE/VT exhibited the best correlation with the mechanical parameters.In conclusion, volumetric capnography, and, specifically, the ratio of alveolar ejection volume to tidal volume allows evaluation and monitoring of ventilatory disturbances in patients with adult respiratory distress syndrome.

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Transfer of Gas by Diffusion and Chemical Reaction in Pulmonary Capillaries

ForsterII¹

1996

Respiratory Physiology

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The Respiratory Dead Space

Cited by 46 publications

References 0 publications

An Investigation of the Pulmonary Function of Paraplegics1

An Investigation of the Pulmonary Function of Paraplegics1

Physiologically based indices of volumetric capnography in patients receiving mechanical ventilation

Transfer of Gas by Diffusion and Chemical Reaction in Pulmonary Capillaries

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