Abstract-The talent cultivation of school enterprise cooperation is an effective way to cultivate high quality and high skilled talents. It is also an important carrier of the cooperative education of industry university research, and is the important content of improving the level of talent training work. Further strengthen the cooperation of schools enterprises, promote the combination between manufacture and learning. Through the construction and design of the talent training mode of the school enterprise cooperation in the agricultural colleges and universities, cultivate high-quality skilled talents, solve the outstanding problems of the teaching process in engineering major of agricultural universities, enhance students' professional ability, method ability and social ability, improve the comprehensive quality of students. Actively explore the advantages and disadvantages of school enterprise cooperation talent cultivation mode, as well as solve the matching problem between the number and quality of skilled talents and social demands. It has a long and profound practical significance to the development of agricultural economy in Tianjin area.