The renal effects and initial characterization of venom from Philodryas nattereri Steindachner, 1870

Abstract

HighlightsWe investigated the effect of P. nattereri venom on the isolated perfused kidney.We study the mechanism of cytotoxicity of venom on renal epithelial cells.We demonstrated P. nattereri venom is composed for 86.3% of proteins.The venom of is capable of changing the kidney functional parameters.

Toxicological and epidemiological studies of scorpion sting cases and morphological characterization of scorpions (Leiurusquin questriatus and Androctonus crassicauda) in Luxor, Egypt

“…The clinical presentations of scorpion envenomation in general prospective are different from those observed in cases of Snakebite. Clinical presentations of Snakebites cases as observed in previous studies were; Local pain at the site of bite, edema, coagulopathies, moderate hypotension, malaise, vomiting, abdominal pain and diarrhea [[22], [23], [24]].…”

Toxicology and snakes in ptolemaic Egyptian dynasty: The suicide of Cleopatra

“…In arid and semiarid regions of South America Philodryas nattereri, commonly called the brown racer belonging to the family Dipsadidae, like the African dipsas, affects the vital functions of their prey by releasing a large number of toxins (enzymes, proteins and peptides) through venom that destabilize the physiological levels of hormones, alter the activity of enzymes, receptors or ion channels, and promote cardiovascular and nervous system imbalance in their prey. Poisoning caused by this species is characterized by local symptoms such as pain, swelling, erythema, bruising, renal failure and regional lymphadenopathy with normal coagulation and produces similar symptoms that can be mistaken with those of African species [ 91 ].…”

Caracterização Histológica Da Glândula De Duvernoy Da Serpente Philodryas Nattereri Steindachner, 1870

“…Philodryas nattereri Steindachner, 1870 é uma espécie de serpentes que está incluída na família Dipsadidae (ZAHER et al, 2009). É uma serpente conhecida popularmente como correcampo ou tabuleiro, sendo encontrada em regiões áridas e semiáridas da América do Sul com predominância no nordeste brasileiro (MESQUITA et al, 2011;NERY et al, 2014). Essa serpente possui dentição opistóglifa, apresentando uma glândula de Duvernoy bem desenvolvida, homóloga às verdadeiras glândulas de veneno de serpentes proteróglifas e solenóglifas.…”

“…A glândula de Duvernoy localiza-se na região temporal, pós-orbital, justaposta à glândula supralabial. Essa glândula está conectada a um dente sulcado, especializado para a inoculação de toxinas (MACKESSY, 2002;NERY et al, 2014).…”