Toxicological and epidemiological studies of scorpion sting cases and morphological characterization of scorpions (Leiurusquin questriatus and Androctonus crassicauda) in Luxor, Egypt

El-Aziz, Fatma El-Zahraa A. Abd; Shehaby, Doaa M. El; Elghazally, Shimaa A.; Hetta, Helal F

doi:10.1016/j.toxrep.2019.03.004

Cited by 19 publications

(23 citation statements)

References 28 publications

(34 reference statements)

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“…A. crassicauda is one of the most venomous scorpions in the world, and that includes Turkey [4][5][6][7] . In this research, we chose repetitive doses of the venom because there have been reports of more than one scorpion sting of a pregnant woman in Turkey.…”

Section: Discussionmentioning

confidence: 99%

“…In spite of developing medical approaches and other measures, in many tropical and subtropical countries scorpion envenomation cases still constitute a serious public health problem that can result in death, especially in  İletişim (Correspondence)  +90 376 2189537 Fax: +90 376 2189541  ozcanozkan@karatekin.edu.tr children [3] . Among scorpion species, Androctonus crassicauda is known as the deadly scorpion and so is of great concern to medicine [4] .…”

Section: Introductionmentioning

confidence: 99%

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Androctonus crassicauda Zehirinin Gebe Sıçanlar ve Yavruları Üzerine Etkileri

Özel¹,

Demırel²,

Ercan³

et al. 2019

Kafkas Univ Vet Fak Derg

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Incidents of scorpion stings are common in Turkey. These cases can cause severe envenomation and so represent an important public health problem. In Turkey, the most venomous species are Leiurus abdullahbayrami and Androctonus crassicauda. There has been no study on the effects of A. crassicauda stings on pregnant rats. Consequently, we investigated the effects of the scorpion venom on pregnant rats and their offspring. The supernatant of the A. crassicauda venom obtained after the venom extraction was dissolved in 7 mL of sterile saline before the experiment, in this way the injection volume was standardized as 1 mL/rat. Pregnant rats were randomly divided into two groups with six animals in each. A. crassicauda venom in 1 mL physiological saline solution (NaCl 0.9%) was subcutaneously injected in rats of the experimental group (EG), while sterile saline solution (1 mL) was subcutaneously administered to the rats of the control group (CG). All injections were applied to each group from the 7 th to the 13 th days of pregnancy, which correspond to the critical organogenesis period. Based on these results, it was shown that the scorpion venom affects the body weight of pregnant rats, the weights of placental tissues and fetuses in the rat model during pregnancy. A. crassicauda venom can induce abortion and cause restrictions in placenta and fetal growth. Therefore, medical professionals should be informed about possible adverse effects and risks in pregnancy.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Androctonus crassicauda Zehirinin Gebe Sıçanlar ve Yavruları Üzerine Etkileri

Özel¹,

Demırel²,

Ercan³

et al. 2019

Kafkas Univ Vet Fak Derg

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“…The papers we reviewed reported cases from Brazil (6), India (5) and Turkey (1). The mean victim's age was 13.25 years old, and in 58.33% it was <10 years old and M/F was 2:1.…”

Section: Epidemiological Findingsmentioning

confidence: 99%

“…Scorpion sting is a public health issue in several countries, particularly in America, the Middle East, India and Africa [1][2][3][4][5][6][7][8][9][10]. Scorpionism epidemiology in the world is poorly known [11], even if it has been estimated that the annual global incidence is about 1.5 million envenomings, resulting in 2600 deaths [12].…”

Section: Introductionmentioning

confidence: 99%

“…Hemiscorpiidae and Scorpionidae are harmful to humans [18,19]. Scorpion venom is a complex structure composed of neurotoxic proteins, salts, acidic proteins and organic compounds, thereby having neurologic, cardiovascular, hematologic and renal side effects, in addition to local effects such as redness, pain, burning and swelling [1]. However, the effect of the scorpion sting is highly dependent on the species, due to the different targets of the venom [20].…”

Section: Introductionmentioning

confidence: 99%

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Autopsy Findings in Case of Fatal Scorpion Sting: A Systematic Review of the Literature

et al. 2020

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Scorpion sting is a public health issue in several countries, particularly in America, the Middle East, India and Africa. The estimated annual global incidence of scorpion envenomings is about 1.5 million, resulting in 2600 deaths. Scorpions are Arthropoda characterized by a tail ending in a terminal bulbous (telson) containing paired venom glands and the stinger. There are 19 known families of scorpions and more than 2200 species, of which about 50 from the families of Buthidae, Hemiscorpiidae and Scorpionidae are harmful to humans. Scorpion venom is a complex structure composed of neurotoxic proteins, salts, acidic proteins and organic compounds, thereby having neurologic, cardiovascular, hematologic and renal side effects, in addition to local effects such as redness, pain, burning and swelling. When the sting is fatal, the mechanism of death is often related to cardiotoxicity with terminal pulmonary edema. However, the cholinergic excess or the neuromuscular excitation can provoke respiratory failure. Sometimes, death is due to an anaphylactic reaction to the envenoming. The purpose of this literature review is to evaluate the autopsy findings in scorpion sting-related deaths in order to better understand the pathophysiological mechanisms underlying them, thus helping pathologists in defining the correct diagnosis.

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