The release of fluoride and other chemical species from a glass-ionomer cement

Wilson, Alan D.; Groffman, D.M.; Kuhn, A. T.

doi:10.1016/0142-9612(85)90107-3

Cited by 140 publications

(47 citation statements)

References 2 publications

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“…Ion release takes part in the formation of the cement matrix and contributes to the therapeutic activity, giving these materials the potential to be used for various clinical applications. The fluoro-alumino-silicate glass-based CGPCs are known for their sustained release of clinically beneficial amounts of fluoride [51,141,142], as shown by Wilson et al [143], who found that the release of fluoride continued for at least 18 months. Fluoride plays an important biological role, particularly in dentistry, and has the effect of improving the resistance of the tooth material to acid attack, decreasing demineralization and increasing remineralization, inhibiting dental decays, and making the cement translucent [144][145][146].…”

Section: Ion Releasementioning

confidence: 99%

The role of poly(acrylic acid) in conventional glass polyalkenoate cements

Alhalawani

Curran

Boyd

et al. 2015

Journal of Polymer Engineering

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Abstract Glass polyalkenoate cements (GPCs) have been used in dentistry for over 40 years. These novel bioactive materials are the result of a reaction between a finely ground glass (base) and a polymer (acid), usually poly(acrylic acid) (PAA), in the presence of water. This article reviews the types of PAA used as reagents (including how they vary by molar mass, molecular weight, concentration, polydispersity and content) and the way that they control the properties of the conventional GPCs (CGPCs) formulated from them. The article also considers the effect of PAA on the clinical performance of CGPCs, including biocompatibility, rheological and mechanical properties, adhesion, ion release, acid erosion and clinical durability. The review has critically evaluated the literature and clarified the role that the polyacid component of CGPCs plays in setting and maturation. This review will lead to an improved understanding of the chemistry and properties of the PAA phase which will lead to further innovation in the glass-based cements field.

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Section: Ion Releasementioning

confidence: 99%

The role of poly(acrylic acid) in conventional glass polyalkenoate cements

Alhalawani

Curran

Boyd

et al. 2015

Journal of Polymer Engineering

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“…The common point in all contemporary theories regarding caries development is that dental caries is an infectious disease, resulting in destruction of the tooth structure, caused by microorganisms, Streptococcus mutans above all (1,2). The most common isolated microorganisms in the mouth of a newborn are Streptococcus salivarius, Staphylococcus epidermidis, Neisseria species and Veillonella species.…”

Section: Introductionmentioning

confidence: 99%

“…Glass-ionomer cements (GIC) are considered anti-cariogenic, bearing in mind the fact that fl uoride has antimicrobial properties (2). In order to improve the antimicrobial characteristics of both conventional and resin-modifi ed glass ionomer cements (RMGIC), antimicrobial compounds have been added.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial effects of conventional glass ionomer cement

Dimkov¹,

Gjorgievska²,

Nicholson³

et al. 2016

BLL

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OBJECTIVES: The antibacterial activity of conventional glass ionomer cement against three different microorganism strains alone and following incorporation of 1, 2 and 3 % Benzalkonium Chloride and Cetylpyridinium Chloride was evaluated. METHODS: Agar diffusion method was used to determine the inhibitory effect of the conventional glass ionomer cement ChemFlex on Streptococcus mutans, Lactobacillus casei and Actinomyces viscosus. Bacterial strains were inoculated into BHIB, and incubated in an anaerobic atmosphere (37 °C). From the bacteria grown in the liquid medium, the density of the inoculum was set to be equivalent to McFarland 2 standard. In Shaedler agar, 350 μL of the bacterial suspension were equally spread. Specimens (4 mm × 6 mm) were prepared from the cement without and with addition of 1, 2 and 3 % Benzalkonium Chloride and Cetylpyridinium Chloride. The inhibition zones were determined after 48 hours, after 2, 7 and 21 days of incubation. RESULTS: The combination ChemFlex + Benzalkonium Chloride has the best effect on the three analysed bacteria. The Benzalkonium Chloride antibacterial compound has a stronger antibacterial effect than Cetylpyridinium Chloride. CONCLUSIONS: Glass ionomer cements can potentially be used as a medium for slow release of active antimicrobial components, and they have the potential to improve clinical outcomes of the cements (Tab. 3, Fig. 3, Ref. 31). Text in PDF www.elis.sk.

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“…It has been shown that this low-level fluoride release is maintained long term. Wilson et al (1985) reported that fluoride was still being released from samples of Chembond (GIC) after 598 days, Forsten (1990) it is therefore desirable to use a material that can be "recharged" with fluoride (Forsten, 1990 Kindelan (1996) showed that the fluoride-releasing bonding agents Ketac-Cem@ (GIC) and Pulpdent OBA@ (polyacid-modified composite) protected extracted human premolars from demineralization, while Rely-a-Bond@ þolyacid-modified composite) did not afford such protection. Basdra et al (1996) (Mitchell, 1992;Banks et aL.,1997;Millett et aL.,1999).…”

Section: 4 Null Ttrypothesismentioning

confidence: 99%