IMPORTANCE Because variation in care on weekends has been reported in many surgical fields, it is of interest if variations were noted for care patterns of rhegmatogenous retinal detachments (RRDs). OBJECTIVE To assess the association between modality of RRD repair and day of the week that patients receive a diagnosis or undergo RRD repair. DESIGN, SETTING, AND PARTICIPANTS A retrospective claims-based cohort analysis was performed of primary RRD surgery for 38 144 commercially insured patients in the United States who received a diagnosis of incident RRD between January 1, 2008, and December 31, 2016, and underwent repair within 14 days of diagnosis. Multinomial regression models were used to assess patients' likelihood of repair with different modalities, logistic regression models were used to assess patients' likelihood of reoperation, and linear regression models were used to assess time from diagnosis to repair. Data analysis was performed from March 9 to September 5, 2019. EXPOSURES Day of the week that the patient received a diagnosis of RRD or underwent RRD repair. MAIN OUTCOME AND MEASURES Modality of repair, time from diagnosis to repair, and 30-day reoperation rate. RESULTS Among the 38 144 patients in the study (23 031 men [60.4%]; mean [SD] age at diagnosis, 56.8 [13.4] years), pneumatic retinopexy (PR) was more likely to occur when patients received a diagnosis of RRD on Friday (relative risk ratio [