The relationship of late potentials to assessment of heart rate variability in post-infarction patients

Kao, Tsair; Hsiao, Hsiang Chiang; Chiu, Hung Wen; Kong, Chi Woon

doi:10.1016/s0167-5273(00)00281-3

Cited by 7 publications

(10 citation statements)

References 22 publications

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“…Abnormal autonomic function is known to predispose to arrhythmias in various clinical and experimental conditions. Sympathovagal imbalance (either increased sympathetic activity or reduced vagal activity) has been shown to be a strong and independent predictor of mortality in patients with myocardial infarction, heart failure, or diabetic neuropathy 17–20 . Conversely, predominance of vagal activity has protective and antifibrillatory effects 17 .…”

Section: Discussionmentioning

confidence: 99%

The Relationship Between Heart Rate Recovery and Heart Rate Variability in Coronary Artery Disease

Evrengül

Tanrıverdi

Köse³

et al. 2006

Noninvasive Electrocardiol

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Section: Discussionmentioning

confidence: 99%

The Relationship Between Heart Rate Recovery and Heart Rate Variability in Coronary Artery Disease

Evrengül

Tanrıverdi

Köse³

et al. 2006

Noninvasive Electrocardiol

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“…Increased sympathetic activity or decreased parasympathetic activity has been proved to be a predictor of mortality and morbidity in patients with myocardial infarction, heart failure or diabetes mellitus with autonomic neuropathy as a complication. Increased parasympathetic activity correlates with a better prognosis of those patients, as it has a protective effect [ 26 , 27 , 28 , 29 ].…”

Section: Discussionmentioning

confidence: 99%

Heart Rate Variability and Heart Rate Recovery as prognostic factors

Grad

2015

Medicine and Pharmacy Reports

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Background and aimHeart rate (HR) can appear static and regular at rest, during exercise or recovery after exercise. However, HR is constantly adjusted due to factors such as breathing, blood pressure control, thermoregulation and the renin-angiotensin system, leading to a more dynamic response that can be quantified using HRV (heart rate variability). HRV is defined as the deviation in time between successive normal heart beat and is a noninvasive method to measure the total variation in a number of HR interval. HRV can serve as measure of autonomic activity of sino-atrial node. The aim of the study was to determine the influence of certain clinical and paraclinical parameters on heart rate recovery after exercise in patients with ischemic heart disease and the relation with HRV using 24 h Holter monitoring.MethodsThe study included 46 patients who were submitted to cardiovascular exercise stress test and also to 24 h Holter EKG monitoring. Subjects had a mean age of 56.2±11.2 years, with a minimum of 25 and a maximum of 79 years. The study included 22 (47.8%) men and 24 (52.2%) women. Statistical analysis was performed using MedCalc software version 14.8.1. Multivariate analysis consisted of the construction of several multiple linear regression models. A p value of 0.05 was considered statistically significant.ResultsThe HRV values (time domain) were all lower in the IHD compared with the group without coronary heart disease, even if the difference is not statistically significant. Also rest and maximal HR values were similar but during the test varies in the sense that those with IHD had higher values of rest and maximal HR and lower HRR, but not statistically significant.ConclusionsHRV is a very easy and safe method if there is an available device and it is used for evaluation of the autonomic nervous system in many cardiovascular diseases, but also in other pathologies.In uncomplicated ischemic heart disease HRV is depressed, but not significant. HRR, which is also considered an indicator of the parasympathetic activity after exercise termination, is also non-significantlly decreased in ischemic patients and the correlation between them is weak. Both HRV and HRR parameters can be easily measured, but the best algorithm of this issue requires further studies, conducted in larger patient populations. Although HRR and HRV are tools to measure the autonomic nervous system activity the relation between them need more studies to be able to quantify the arrhythmogenic risk.

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“…The prognostic value of HRV has been shown in several large samples of patients with coronary heart disease (Kao et al 2000;Gerritsen et al 2001) and in normal elderly population (Tsuji et al 1994). In any event, the capability of HRV to predict outcome in normal subjects is not as well established as in patients with coronaropathy.…”

Section: Discussionmentioning

confidence: 99%

“…The predominance of sympathetic tone in cardiac activity induces tachycardia and reduced beat-to-beat variations, while parasympathetic nerve activity acts to slow heart rate and increase HRV (Akselrod et al 1985). Reduction of HRV, and expression of increased sympathetic tone, can be found to have negative prognostic value in a number of important pathologic conditions such as post-infarction, diabetic autonomic neuropathy, systemic hypertension (Porges 1972;Knave et al 1979;Juutilainen et al 1990;Graham et al 2000b;Kao et al 2000;Kaftan and Kaftan 2000;Yan et al 2000;Gerritsen et al 2001;Karavanaki-Karanassiou 2001;Mussalo et al 2001;Pagani and Lucini 2001;Sosnwski 2002) and in a normal elderly population (Tsuji et al 1994). Finally, in normal human volunteers (Sastre et al 1998), some authors revealed that exposure to ELF-EMF reduced HRV.…”

Section: Introductionmentioning

confidence: 99%