The Relationship between the Micromeritic Properties of Mixture and Raw Materials: Microcrystalline Cellulose and <i>Herba sarcandrae</i> Extract

Abstract

Microcrystalline Cellulose andHerba Sarcandraewere used to study the properties and relationship of powders before and after blending. The theoretical values of the physical quantities of the binary mixture were calculated based on the random mixing theory, The measured values of particle size specific surface area, pore volume and angle of repose of binary mixture had larger values than that of theoretical calculations. Whereas, tapped density and bulk density had a smaller value. The results suggested that the mixing behavior was not a complete random, arbitrary or simple superposition of the operation for coarse and sticky particles. The mixing process would create novel particles and physical quantities of novel particles exist regular changes.

Mechanistic Basis for the Role of Binary Mixtures Flowability and Related Factors in the Processability and Performance of High Shear and Extrusion Granulation

“…Granulation also known as agglomeration, pelletisation, is defined as a process of agglomerating whereby small particles are gathered together into larger, semi-permanent aggregates [1]. The granulation process is widely industrially-applied, including mineral processing, agricultural products, detergents, pharmaceuticals, foodstuffs and speciality chemicals [2][3].…”