“…However, previous reports indicated no significant difference in extrathyroidal extension, LN metastasis, and multifocality between the two groups. 26 , 27 , 28 We think that the lack of association between the BRAF V600E mutation and some poor clinicopathologic factors might have resulted from the small number of cases and/or large number of micro-PTCs (28 of 72, 38.9%), and different prevalence of BRAF V600E mutation. Therefore, further studies with a larger patient population may be necessary to determine clinical utilities such as diagnosis and prognosis in patients with PTC.…”