The Relationship between Smoking Behavior and the Incidence of Tuberculosis at the Medan Sunggal Public Health Center

Abstract

A B S T R A C TBackground Prostate cancer is the most common cancer in men worldwide and rankssecond in the Laboratory of Anatomical Pathology, Dr. Mohammad Hoesin with thehighest incidence, especially at the age of more than 60 years. Factors that play a roleas a prognostic factor and therapy in prostate carcinoma, including VEGF. The roleof VEGF expression in prostate carcinoma as a prognostic and histopathological factorwhich is an important predictor for the progression of prostate carcinoma. This studyaims to determine the relationship between VEGF expression and Gleason score inprostate carcinoma. Method This study was a cross-sectional observational study.Thirty samples diagnosed with prostate adenocarcinoma were derived from the resultsof the tranurethral resection of the prostate (TRUP) and prostatectomy. Samples weretaken from the archives in the Anatomic Pathology section of Dr. Mohammad HoesinPalembang (period January 1, 2011 to December 31, 2013. Then the sample wasstained with VEGF antibody, identified and analyzed the VEGF relationship with theGleason.z score. Results The positivity of VEGF expression in prostateadenocarcinoma tended to be more prevalent in the Gleason score group ≥ 7 (43.3%)than in the Gleason score group <(10%). There was no significant relationship betweenVEGF expression and high Gleason score (p> 0.05). Conclusion There was nosignificant relationship between VEGF expression and Gleason score in prostateadenocarcinoma