The relationship between platelet to lymphocyte ratio and the clinical outcomes in ST elevation myocardial infarction underwent primary coronary intervention

Abstract

The platelet to lymphocyte ratio (PLR) has been investigated as a new predictor for cardiovascular risk. The aim of the present study was to investigate the prognostic role admission PLRat admission in predicting in-hospital and early mortality in patients presenting with ST segment elevation myocardial infarction (STEMI). A total of 639 consecutive patients with STEMI who underwent primary percutaneous coronary intervention (PCI) were included. The study population was divided into tertiles on the basis of PLR values at the admission. A high PLR (N = 213) was defined as a value in the upper third tertile (PLR >174.9) and a low PLR (N = 426) was defined as any value in the lower two tertiles (PLR ≤ 174.9). The patients were followed for clinical outcomes for up to 6 months after discharge. In Kaplan-Meier survival analysis, the rate of 6-month all-cause deaths was 7% in the high PLR group versus 3% in the low PLR group (P = 0.03). In multivariate analyses, a significant association was noted between high PLR levels and the adjusted risk of 6-month all-cause deaths (odds ratio = 2.51, 95% confidence interval = 1.058-5.95; P = 0.03). PLR is a readily available clinical laboratory value associated with 6-month all-cause death in patients with STEMI who undergo primary PCI.

Increased Platelet to Lymphocyte Ratio is Related to Slow Coronary Flow

“…Moreover, they reported that the PLR significantly predicted all-cause mortality independent of the platelet or lymphocyte counts alone. Furthermore, in another study Ugur et al 24 found that higher PLR level was associated with increased risk of in-hospital adverse events and also 6-month all-cause mortality in patients with ST-segment elevation myocardial infarction after primary percutaneous coronary intervention. A recent study 25 showed that the PLR was significantly higher in patients with SCF.…”

Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis acute appendicitis

“…In the present study, we did not find an important difference in the MPV values among AA and healthy subjects. As a combination of both platelet and lymphocyte counts, the PLR was introduced as a potential marker to establish inflammation in cardiac and oncologic disorders (26). However, any studies till date have been investigated in AA.…”

Platelet to lymphocyte ratio in the prediction of adverse outcomes after acute coronary syndrome: a meta-analysis

“…Ugur et al . found that there was a significant association between high PLR levels and the adjusted risk of 6-month all-cause deaths in ST elevation myocardial infarction underwent primary coronary intervention, while with no difference in in-hospital mortality among patients with different PLR levels10. Although most studies demonstrated the positive association between PRL and ACS adverse outcomes, there are still some discrepancies.…”