The relationship between performance status and sleep quality in cancer patients.

Abstract

e20544 Background: Poor sleep is common, and is linked to impaired cognitive, psychological, and physical functioning and a lower quality of life. The purpose of this study is to measure quality of sleep in cancer patients and determine the relationship between quality of sleep and performance status. Methods: Patients with cancer (n=139) were recruited at the public hospital between November 2011 and January 2012 and asked to complete the Pittsburgh Sleep Quality Index (PSQI) and the Eastern Cooperative Oncology Group (ECOG) performance status (PS) questionnaires. Twenty patients repeated the questionnaires after 3 months. For the purpose of this study PSQI global score >5 was considered insomnia. PS score 0-1 was considered good, and PS 2-4 was considered poor. Results: The mean age of participants was 55±11 years, 56% were women, 78% were ethnic minority, 77% had advanced cancer, and 71% were undergoing cancer treatment. Among all patients, 73% reported good PS. Median PSQI score was 7 (IQR 4; 11) and 62% had insomnia. Sleep medication was used by 25%. Patients with poor PS had worse PSQI score (Mann-Whitney test, p< 0.0001), and 7.34 (95%CI 2.11-25.49) higher odds of insomnia (p=0.0002) compared to patients with good PS.(Table1) No significant correlation was found between insomnia and gender, ethnicity, primary tumor type, tumor stage, or treatment status. Conclusions: The incidence of insomnia among cancer patients is high. There is a higher incidence of sleep disturbance and worse sleep quality among patients with poorer performance status. [Table: see text]

Sleep Quality and Associated Factors Among Adult Cancer Patients Under Treatment at Oncology Units in Amhara Region, Ethiopia

“…This performance status difference between the Italian and current study participants makes the prevalence of poor sleep quality high in the present study because pieces of evidence indicated that patients with higher scores of ECOG performance status are more likely to become poor sleepers. 14 , 35 In Denmark, patients who had distant metastasis cancer were excluded from the study, which lowers the prevalence of poor sleep quality in that study. Similarly, the prevalence of poor sleep quality in the current study was also higher than the studies conducted in India (57.6%), Turkey (40.4%), Iran (51.4%), and America (64%).…”

“…Performance status: by using the Eastern Cooperative Oncology Group (ECOG) performance status scale, a grade of 0–1 indicates good performance status and a grade of 2–4 indicates poor performance status. 35 …”

“…34 Moreover, poor functional performance status, poor social support, and higher body mass index are significant factors associated with poor sleep quality. 14 , 35–37 …”

Depression, anxiety and their associated factors among patients with cancer receiving treatment at oncology units in Amhara Region, Ethiopia: a cross-sectional study

“…Performance status: by using the Eastern Cooperative Oncology Group (ECOG) performance status scale, a grade of 0–1 indicates good performance status and a grade of 2–4 indicates poor performance status. 36 …”