The relationship between Dietary approaches to stop hypertension diet adherence and inflammatory factors and insulin resistance in overweight and obese women: A cross-sectional study

Taheri, Akram; Mirzababaei, Atieh; Setayesh, Leila; Yarizadeh, Habib; Shiraseb, Farideh; Imani, Hossein; Clark, Cain C. T.; Mirzaei, Khadijeh

doi:10.1016/j.diabres.2021.109128

Cited by 9 publications

(6 citation statements)

References 38 publications

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“…Athletes have utilized non-steroidal anti-inflammatory medicines (NSAIDs), such ibuprofen, to treat the pain and symptoms of muscular injury26. Our findings demonstrate that although ibuprofen use has some beneficial effects, there is no conclusive proof that it benefits muscular function or prevents muscle injury 27 . Activity first inhibits the expression of the MEK-ERK gene at the molecular level, which then prevents the production of protein in the human skeletal muscle 9 .…”

Section: Discussioncontrasting

confidence: 55%

During Resistance Training the Effect of Ibuprofen on Muscle Hypertrophy Regarding Strength and Soreness. A Population Based Cross-Sectional Study

Hussain,

Umar,

Shuja

et al. 2023

PJMHS

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Background: Non-steroidal anti-inflammatory medicines (NSAIDs) are frequently used to speed up post-exercise recovery and lessen discomfort and soreness in muscles. There is a concept that Ibuprofen at high doses has been found to prevent the production of muscle proteins following a session of resistance training. Aims and Objectives: To examine the effects of 400 mg/ day dose of ibuprofen on muscular hypertrophy and strength following resistance exercise. Study Design: This was a population based cross-sectional study. Place and Duration: Present study was conducted in different work out gyms of Lahore region from October 2022 to April 2023. Research Rationale: The combined findings of in vitro and human studies indicate that NSAIDs may blunt the early skeletal muscle responses to exercise. Their widespread use is due to their effectiveness in reducing inflammation, fever, and discomfort. Methodology: Total 100 participants were in this study and all of them provided written informed consent and completed questionnaires about their past training experiences. 70 males and 30 females 20-30 years of age trained their right and left biceps on alternate days 6 sets of 4–10 repetitions, 5 days in week–1, for 8 weeks. All subjects before selection for study completed medical examination blood analysis and health history questionnaires. All participants were received, 400 mg/day of ibuprofen after training their left or right arm. Before and after training muscle thickness of both biceps was measured using ultrasound, and 1 repetition maximum (1 RM) arm curl strength was assessed on both arms. The weights of the dumbbells were chosen so that the required number of repetitions would result in training till failure on each individual set.

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Section: Discussioncontrasting

confidence: 55%

During Resistance Training the Effect of Ibuprofen on Muscle Hypertrophy Regarding Strength and Soreness. A Population Based Cross-Sectional Study

Hussain,

Umar,

Shuja

et al. 2023

PJMHS

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“…It is suggested that diet and physical activity significantly influence insulin sensitivity. Importantly, the role of dietary patterns in relation to IR is remarkable and quite well proven [12][13][14][15]. Physical activity, being an integral part of any balanced lifestyle, is recommended for PCOS women.…”

Section: Introductionmentioning

confidence: 99%

Physical Activity, Rather Than Diet, Is Linked to Lower Insulin Resistance in PCOS Women—A Case-Control Study

et al. 2023

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Insulin resistance (IR) is a prominent feature of polycystic ovary syndrome (PCOS). The importance of lifestyle interventions in the management of PCOS is strongly highlighted and it is suggested that diet and physical activity may significantly influence insulin sensitivity. Therefore, we evaluated the link between diet and physical activity and various indices of insulin resistance, including adipokines secreted by the adipose tissue in 56 PCOS and 33 healthy control women. The original food frequency questionnaire and Actigraph GT3X-BT were used to assess the adherence to the diet recommended in IR and the level of physical activity, respectively. We observed that higher levels of physical activity were associated with lower HOMA-IR and a greater chance of its normal value in PCOS group. No such relationship was observed for other IR indices and adipokines or for the diet. However, we noted a strong correlation between HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) and HOMA-AD (Homeostatic Model Assessment-Adiponectin) in PCOS women. Additionally, when we used HOMA-AD we observed a higher prevalence of IR among PCOS women. Our study supports the beneficial role of physical activity in the management of insulin resistance in PCOS women. Moreover, our findings indicate that HOMA-AD may be a promising surrogate marker for insulin resistance assessment in women with PCOS.

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“…In a randomized controlled trial in 2021, 12-week following DASH diet with and without exercise on anthropometric indices, DASH diet plus exercise resulted in significantly lower weight and WHR, although at the end of the study, the inter-group differences were not statistically significant [ 57 ]. Moreover, a cross-sectional study on 305 overweight and obese women showed that adherence to DASH diet was inversely associated with greater weight reduction [ 58 ]. Soltani et al [ 42 ] in a meta-analysis of randomized controlled trials on the effect of low calorie DASH diet on weight (N = 10), BMI (N = 6) and WC (N = 2) demonstrated its lowering effect on the studied anthropometric measures.…”

Section: Discussionmentioning

confidence: 99%

“…Studies investigating the effect of DASH diet with other inflammatory biomarkers are few. Taheri et al [ 58 ] showed that DASH diet compared with other dietary pattern did not affect serum levels of MCP-1. A systematic review on 16 observational and 13 interventional studies concluded that plant-based dietary patterns (such as Mediterranean or DASH diet) reduce inflammatory biomarkers such as serum hs-CRP, TNF-α and IL-6 [ 74 ].…”

Section: Discussionmentioning

confidence: 99%

The effect of DASH diet on glycemic response, meta-inflammation and serum LPS in obese patients with NAFLD: a double-blind controlled randomized clinical trial

et al. 2023

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Background As dietary approaches to stop hypertension (DASH) dietary pattern has been shown to be effective in hypertension and obesity, the present study investigated the effects of following DASH diet on glycemic, meta-inflammation, lipopolysaccharides (LPS) and liver function in obese patients with non-alcoholic fatty liver disease (NAFLD). Methods In this double-blind controlled randomized clinical trial, 40 obese patients with NAFLD were randomly allocated into either “DASH diet” (n = 20) or calorie-restricted diet as "Control” (n = 20) group for 8 weeks. Anthropometric measures, blood pressure, glycemic response, liver enzymes, toll-like reseptor-4 (TLR-4) and monocyte chemoattractant protein (MCP-1) and LPS as well as Dixon's DASH diet index were assessed at baseline and after 8 weeks. Results After 8 weeks, although all obesity indices decreased significantly in both groups, the reduction in all anthropometric measures were significantly greater in DASH vs control group, after adjusting for baseline values and weight change. Fasting glucose level decreased in both group, however, no inter-group significant difference was found at the end of study. Nevertheless, serum levels of hemoglobin A1c (HbA1c), TLR-4, MCP-1 and LPS as well as aspartate aminotransferase (AST) decreased significantly in DASH group, after adjusting for baseline values and weight change (p < 0.001, p = 0.004, p = 0.027, p = 0.011, and p = 0.008, respectively). The estimated number needed to treats (NNTs) for one and two grade reductions in NAFLD severity following DASH diet were 2.5 and 6.67, respectively. Conclusion Adherence to DASH diet could significantly improve weight, glycemia, inflammation and liver function in obese patients with NAFLD.

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The relationship between Dietary approaches to stop hypertension diet adherence and inflammatory factors and insulin resistance in overweight and obese women: A cross-sectional study

Cited by 9 publications

References 38 publications

During Resistance Training the Effect of Ibuprofen on Muscle Hypertrophy Regarding Strength and Soreness. A Population Based Cross-Sectional Study

During Resistance Training the Effect of Ibuprofen on Muscle Hypertrophy Regarding Strength and Soreness. A Population Based Cross-Sectional Study

Physical Activity, Rather Than Diet, Is Linked to Lower Insulin Resistance in PCOS Women—A Case-Control Study

The effect of DASH diet on glycemic response, meta-inflammation and serum LPS in obese patients with NAFLD: a double-blind controlled randomized clinical trial

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