The relationship between complete blood count parameters and Fontaine’s Stages in patients with peripheral arterial disease

Demirtaş, Sinan; Karahan, Oğuz; Yazici, Suleyman; Güçlü, Orkut; Çalışkan, Ahmet; Yavuz, Celal; Küçüker, Aslıhan; Mavitaş, Binali

doi:10.1177/1708538114522227

Cited by 42 publications

(41 citation statements)

References 22 publications

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“…Zalawadiya et al measured RDW in 6,950 participants from general population and after adjustment for potential confounders they showed that, there is a direct relationship between RDW and prevalence of PAD . Demirtas et al studied 82 PAD patients and showed that RDW increased incrementally with the progression of PAD severity stages …”

Section: Role Of Rdw In Peripheral Artery Disease and Rdwmentioning

confidence: 99%

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The diagnostic and prognostic value of red cell distribution width in cardiovascular disease; current status and prospective

et al. 2019

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The red blood cell distribution width (RDW) is an index of the heterogeneity of circulating red blood cell size, which along with other standard complete blood count (CBC) parameters are used to identify hematological system diseases. Besides hematological disorders, several clinical studies have shown that an increased in the RDW may be associated with other diseases including acute pancreatitis, chronic kidney disease, gastrointestinal disorders, cancer, and of special interest in this review, cardiovascular disease (CVD). The diagnostic and prognostic value of RDW in different CVD (acute coronary syndrome, ischemic cerebrovascular disease, peripheral artery disease, atrial fibrillation, heart failure, and acute ischemic stroke) has been reviewed in this article, to provide an understanding how its measurement may be applied to improve the management of these conditions.

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Section: Role Of Rdw In Peripheral Artery Disease and Rdwmentioning

confidence: 99%

“…46 Demirtas et al studied 82 PAD patients and showed that RDW increased incrementally with the progression of PAD severity stages. 47…”

Section: Role Of Rdw In Peripheral Artery Disease and Rdwmentioning

confidence: 99%

The diagnostic and prognostic value of red cell distribution width in cardiovascular disease; current status and prospective

et al. 2019

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“…Increased MPV has been reported to correlate with intracoronary thrombus burden in the IRA before mechanical reperfusion, in-hospital major adverse cardiovascular events in patients with STEMI undergoing PCI [7,8], and 1-year incidence of death or myocardial infarction in patients with acute coronary syndrome undergoing PCI [9]. Furthermore, recent studies by Demirtas et al [10] and Yavuz et al [11] showed there is an interaction between MPV and disease severity in many types of arterial-occlusive diseases, such as peripheral artery disease and thromboangiitis obliterans. However, the association between MPV and myocardial reperfusion in patients with STEMI and successful epicardial reperfusion after PCI has not been fully investigated.…”

Section: Introductionmentioning

confidence: 96%

Association of mean platelet volume with impaired myocardial reperfusion and short-term mortality in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Lai

Chen

Yang

et al. 2016

Blood Coagulation &Amp; Fibrinolysis

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Impaired myocardial reperfusion, defined angiographically by myocardial blush grade (MBG) 0 or 1, is associated with adverse clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI). The aim of this study was to investigate the impact of admission mean platelet volume (MPV) on the myocardial reperfusion and 30-day all-cause mortality in patients with STEMI with successful epicardial reperfusion after primary percutaneous coronary intervention (PCI). A total of 453 patients with STEMI who underwent primary PCI within 12 h of symptoms onset and achieved thrombolysis in myocardial infarction (TIMI) 3 flow at infarct-related artery after PCI were enrolled and divided into two groups based on postinterventional MBG: those with MBG 2/3 and those with MBG 0/1. Admission MPV was measured before coronary angiography. The primary endpoint was all-cause mortality at 30 days. MPV was significantly higher in patients with MBG 0/1 than in patients with MBG 2/3 (10.38 ± 0.98 vs. 9.59 ± 0.73, P < 0.001). The cumulative 30-day all-cause mortality rate was significantly higher in the groups with high MPV and MBG 0/1 (6.8 vs. 1.5%, P = 0.005, 7.6 vs. 1.9%, P = 0.006, respectively). Multivariate logistic regression analysis demonstrated MPV was independently associated with postinterventional impaired myocardial reperfusion (odds ratio 2.684, 95% confidence interval 2.010-3.585, P < 0.001) and 30-day all-cause mortality (hazard ratio 1.763, 95% confidence interval 1.009-3.079, P = 0.046). Increased MPV on admission is an independent predictor of impaired myocardial reperfusion and short-term mortality in patients with STEMI with successful epicardial reperfusion after primary PCI. Admission MPV may be additive to conventional risk factors in patients with STEMI undergoing PCI.

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“…A prospective study by Kullar et al [42] reviewed the relationship between post-operative NLR values and graft failure that can develop afterwards and postoperative high NLR values were found to be associated with graft failure. Another study by Demirtaş et al [43] prospectively reviewed 50 patients with the diagnosis of new peripheral arterial occlusion. In this study preoperatively taken complete blood count parameters were examined according to Fontaine's classification.…”

Section: Discussionmentioning

confidence: 99%

Neutrophil-to-lymphocyte ratio in occlusive vascular diseases: the literature review of the past 10 years

Küçük¹,

Kocayiğit²,

Günel³

et al. 2016

World Journal of Emergency Medicine

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The relationship between complete blood count parameters and Fontaine’s Stages in patients with peripheral arterial disease

Cited by 42 publications

References 22 publications

The diagnostic and prognostic value of red cell distribution width in cardiovascular disease; current status and prospective

The diagnostic and prognostic value of red cell distribution width in cardiovascular disease; current status and prospective

Association of mean platelet volume with impaired myocardial reperfusion and short-term mortality in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Neutrophil-to-lymphocyte ratio in occlusive vascular diseases: the literature review of the past 10 years

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