The relationship between behavior acquisition and persistence abilities: Involvement of adult hippocampal neurogenesis

Abstract

Doublecortin (DCX)‐Calretinin (CLR) immunolabeling of the hippocampal dentate gyrus of a 4 month old male mice (Mus musculus). DCX+ (red) and CLR+ (green) neurons in a section from a control (no treatment) mouse, where both DCX+/CLR+ and DCX+/CLR+ can be appreciated. This dual labeling lets to count two different subpopulation of immature, differentiating neurons in two successive stages of maturation with one double immunohistochemistry reaction. Cell counts were performed in these type of sections by using the U‐disector and confocal microscopy. The cover image, by J.L. Trejo et al., is based on the Research Article The relationship between behavior acquisition and persistence abilities: Involvement of adult hippocampal neurogenesis, DOI: .

Enriched Environment Increases PCNA and PARP1 Levels in Octopus vulgaris Central Nervous System: First Evidence of Adult Neurogenesis in Lophotrochozoa

“…In insect brain, cell proliferation is detectable in the mushroom bodies Malaterre et al, 2002;Scotto-Lomassese et al, 2003;Cayre et al, 2007) involved in sensory discrimination, learning, memory, control of complex behavioral repertoires, and spatial orientation (Mizunami et al '93;Strausfeld et al,'98). In mammals, the dentate gyrus of hippocampus is considered one of the canonical sites of adult neurogenesis (Kempermann and Gage, 2000;van Praag et al, 2002;Choi et al, 2016) involved in memory, spatial navigation, and learning (Leuner and Gould, 2010;Gradari et al, 2016). We found that the neurogenic sites of octopuses, insects, and mammals share anatomical and functional similarities.…”