The Relationship Among Carbon Dioxide Pneumoperitoneum, Vasopressin Release, and Hemodynamic Changes

Mann, C.; Boccara, Gilles; Pouzeratte, Y.; Eliet, Jacob; Gal, Claudine Serradeil–Le; Vergnes, C.; Bichet, Daniel G.; Guillon, Gilles; Fabré, J; Colson, P

doi:10.1213/00000539-199908000-00003

Cited by 63 publications

(41 citation statements)

References 21 publications

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“…Pneumoperitoneum using CO 2 for laparoscopic surgery causes a rapid and immediate increase in plasma catecholamines and vasopressin, [2,3] possibly due to an increase in intraperitoneal pressure and stimulation of the peritoneum by CO 2 . The increase in these stress hormones induces a cardiovascular response characterized by abrupt elevations of arterial pressure, SVR and HR [1].…”

Section: Discussionmentioning

confidence: 99%

“…The increase in mean arterial pressure (MAP) and systemic vascular resistance (SVR) occurring immediately at the induction of pneumoperitoneum is suggestive of involvement of the sympathetic nervous system [1]. These hemodynamic responses are due to increased release of catecholamines, vasopressin, or both [2,3]. These complications are not serious enough in ASA I and II patients, but an exaggerated response to pneumoperitoneum has been reported in elderly and ASA III patients particularly with compromised cardiovascular system physiology.…”

Section: Introductionmentioning

confidence: 99%

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Comparative Evaluation of Dexmedetomidine and Esmolol on Hemodynamic Responses During Laparoscopic Cholecystectomy

Srivastava

Nagle

Agrawal

et al. 2015

JCDR

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Background: The advent of laparoscopic surgery has benefited the patient and surgeon; however creation of pneumoperitoneum for same has bearings during the perioperative period. These effects of pneumoperitoneum are associated with significant haemodynamic changes, increasing the morbidity of the patient. Aim:The present study compared the efficacy of dexmedetomidine and esmolol on hemodynamic responses during laparoscopic cholecystectomy Materials and Methods: A total of 90 patients aged 20-60 y, American Society of Anaesthesiologists (ASA) physical status I or II, of either sex, planned for laparoscopic cholecystectomy were included. The patients were randomly divided into three groups of 30 each. Group D received dexmedetomidine loading dose 1 mcg/kg over a period of 15 min and maintenance 0.5 mcg/kg/h throughout the pneumoperitoneum. Group E received esmolol loading dose 1 mg/kg over a period of 5 min and maintenance 0.5 mg/kg/h throughout the pneumoperitoneum. Group C received same volume of normal saline.Measurements: Heart rate (HR), systolic blood pressure, diastolic blood pressure and mean arterial pressure (MAP) were recorded preoperative, after study drug, after induction, after intubation, after pneumoperitoneum at 15 min intervals, post pneumoperitoneum and postoperative period after 15 min. Propofol induction dose, intraoperative fentanyl requirement and sedation score were also recorded.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparative Evaluation of Dexmedetomidine and Esmolol on Hemodynamic Responses During Laparoscopic Cholecystectomy

Srivastava

Nagle

Agrawal

et al. 2015

JCDR

View full text Add to dashboard Cite

show abstract

“…A maioria dos estudos relata um aumento na pressão arterial média (PAM) após a insuflação da cavidade abdominal para a criação de um pneumoperitônio [33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49] . Alguns estudos observaram um aumento na concentração plasmática do hormônio antidiurético (ADH) após a criação do pneumoperitônio 40,50,51 , suficiente para determinar o aumento da PAM e da SVR por vasoconstrição 40,52,53 . Acriação do pneumoperitônio com a insuflação de CO 2 leva a um aumento da concentração plasmática da renina [54][55][56] e da aldosterona 55 e da noradrenalina.…”

Section: Resultsunclassified

Estudo comparativo dos efeitos hemodinâmicos e ventilatórios da ventilação controlada a volume ou a pressão, em cães submetidos ao pneumoperitônio

Carraretto¹,

Vianna²,

Almeida³

et al. 2005

Rev. Bras. Anestesiol.

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“…In fact, the hemodynamic effects of pneumoperitoneum have been likened to that of heart failure [58]. Besides IAH, other major influences on cardiocirculatory status during laparoscopic surgery include posture and carbon dioxide insufflation [56, 58,59,60]. Head-up position is associated with a decrease in preload and an increase in afterload while the opposite effects are seen with head-down position [56].…”

Section: Special Situations With Laparoscopymentioning

confidence: 99%

Intra-abdominal hypertension and abdominal compartment syndrome

Sieh

Chu

Wong

2001

Langenbeck's Archives of Surgery

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Akin to compartment syndrome in extremities, the pathophysiological effects of increased intra-abdominal pressure developed well before any clinical evidence of compartment syndrome. These effects include cardiovascular, pulmonary, renal and intracranial derangement, reduction of intestinal and hepatic blood flow, and reduction of abdominal wall compliance. Although abdominal compartment syndrome is more commonly noted in patients with abdominal trauma, it is now evident that non-trauma surgical patients could also develop the condition. Early initiation of treatment for intra-abdominal hypertension is currently advocated in view of the possibility of subclinical progress to the full-blown abdominal compartment syndrome.

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The Relationship Among Carbon Dioxide Pneumoperitoneum, Vasopressin Release, and Hemodynamic Changes

Cited by 63 publications

References 21 publications

Comparative Evaluation of Dexmedetomidine and Esmolol on Hemodynamic Responses During Laparoscopic Cholecystectomy

Comparative Evaluation of Dexmedetomidine and Esmolol on Hemodynamic Responses During Laparoscopic Cholecystectomy

Estudo comparativo dos efeitos hemodinâmicos e ventilatórios da ventilação controlada a volume ou a pressão, em cães submetidos ao pneumoperitônio

Intra-abdominal hypertension and abdominal compartment syndrome

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