The relation of serum γ-glutamyl transferase levels and coronary collateral circulation in patients with chronic coronary total occlusion

Abstract

Increased serum GGT levels independently predict poorly developed CCC in patients with coronary CTO. Our results show that GGT is a simple and readily available marker for sufficiency of CCC in patients with CTO.

γ-Glutamyl Transferase Activity and the Burden of Coronary Atherosclerosis in Patients With ST-Segment Elevation Myocardial Infarction

“…[20][21][22][23][24] High-GGT activity in patients with CAD might be the result of oxidative stress in atherosclerotic plaques. 25 There is evidence that cellular GGT helps maintain intracellular antioxidant defense systems. 26 The GGT acts as a mediator in transport of extracellular glutathione into most types of cells.…”

Impact of serum alkaline phosphatase level on coronary collateral circulation

“…Prolonged myocardial ischaemia plays a pivotal role in the development of CCC, although not all aspects of the mechanisms underlying the development of coronary collaterals are thoroughly understood [1][2][3][4]. The variance between patients regarding coronary collateral development has prompted research on the different clinical and laboratory factors that may influence this phenomenon [5][6][7][8][9][10]. Serum alkaline phosphatase (ALP) level has been shown to be a prognostic factor in myocardial infarction and stroke due to its promotion of vascular calcification [11,12].…”