The Relation Between Constitutional Skin Color and Photosensitivity Estimated from UV-Induced Erythema and Pigmentation Dose-Response Curves

Westerhof, W.; Estevez-Uscanga, Oscar; Meens, Joes; Kammeyer, Arthur; Durocq, Muriel; Cario, Irina

doi:10.1111/1523-1747.ep12874671

Cited by 118 publications

(128 citation statements)

References 7 publications

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“…o Discussion Both instruments used in this study are new, fully portable, easy to operate and offer objective color values quickly. Recent studies actually report the usefulness of a tristimulus colorimeter in the study of the quantitative evaluation of ultraviolet(UV)-induced erythe ma and tanning [1,5,6], intensity of irritant or allergic dermatitis [2,4], skin blanching induced by topical corticosteroid [7,8] and argon laser treatment of port wine stains [9].…”

Section: Resultsmentioning

confidence: 99%

Comparison of Narrow-Band Reflectance Spectrophotometric and Tristimulus Colorimetric Measurements of Skin Color

Takiwaki¹,

Overgaard²,

Serup³

1994

Skin Pharmacol Physiol

104

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Two types of portable reflectance instruments, tristimulus colorimeters (Chroma Meter CR-200®) and narrow-band spectro-photometers (Dermaspectrometer®), have recently become available for the quantification of skin color. In order to know the difference and the relationship between the different color systems, the CIE L*a*b* system and the erythema melanin (E/M) indices, respectively, adopted by the two, the variations in skin color were measured at 23 different anatomical sites of 10 healthy Caucasian male subjects. The reddish tint of the skin color of the face, palm and sole was readily detected by either of them in the increase in the a* value or in the E index, and a strong linear correlation (r = 0.92, p < 0.001) was noted between the two values. The fair color appearance of the trunk was detected in the high L* value and in the low M index, but the correlation between the two was much less significant (r = -0.56, p < 0.001). Although the mean b* values were highest in the trunk, they are significantly lower on the non-light-exposed side than those on the light-exposed side of the arm. The correlation between the b* value and the M index was weak.

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Section: Resultsmentioning

confidence: 99%

Comparison of Narrow-Band Reflectance Spectrophotometric and Tristimulus Colorimetric Measurements of Skin Color

Takiwaki¹,

Overgaard²,

Serup³

1994

Skin Pharmacol Physiol

104

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“…They are quite convenient for a quick mea surement of the skin color by their portability and the easiness to operate. They have been applied successfully to the evaluation of the patch test reaction [6][7][8], UV-induced erythe ma and/or tanning [9][10][11], and topical anti inflammatory drug activity [12]. We tried to apply them to the numerical expression of the lesional color of psoriasis in this study.…”

Section: Discussionmentioning

confidence: 99%

Measurement of Color Parameters of Psoriatic Plaques by Narrow-Band Reflectance Spectrophotometry and Tristimulus Colorimetry

Takiwaki

Serup

1994

Skin Pharmacol Physiol

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Color parameters were measured on 50 psoriatic plaques in 10 patients, after scoring the amount of scales on them by inspection, with a narrow-band reflectance spectrophotometer (erythema/melanin index expression) and tristimulus colorimeter (CIE L*a*b* expression). Both erythema index and a* (redness) were highest in the group of erythematous plaque with little scale (twice as high as in controls) and decreased significantly as the plaques were covered with thicker scale, while L* (brightness) changed in just the opposite fashion of a*. These portable ‘color indicators’ can be utilized to express the appearance of psoriatic plaques quantitatively, especially the extent of erythema and the amount of the scale on it.

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“…As proven many years ago [9], the steepness of dose-response curves for erythema, as measured by a colorimeter 24 h after irradiation of the skin, is the best measure of the response of the skin to UV irradiation. We used the UVB-induced erythema as a model of inflammation, irrespective of the possible role played by UV light in the pathogenesis of rosacea.…”

Section: Discussionmentioning

confidence: 99%

Topical Metronidazole Does Not Abate UVB-Induced Erythema

Guarrera

Brusati²,

Rebora³

2001

Dermatology

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Background: The capacity of topical metronidazole to reduce erythema severity scores in rosacea has been attributed to its anti-inflammatory activity. Methods: Nine healthy subjects were irradiated on three 1-cm² areas on their volar forearm with 2 MEDs of UVB. Twenty-four hours later, one of the irradiated areas was treated daily with metronidazole 1% vanishing cream, one with the vehicle only and the third was left untreated (control). The intensity of erythema was measured, at 24, 48, 72 and 96 h after irradiation, by a Chromameter CR200 (Minolta, Japan) and expressed in the L*a*b* system. The a* parameter was taken as the measure of redness. Results: Overall, redness diminished over time in a linear way, but treatments did not influence it significantly. Conclusion: In our vehicle, metronidazole 1% cream failed to abate the UVB-induced erythema. An activity other than the anti-inflammatory one should be suggested to explain the topical metronidazole efficacy in rosacea.

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The Relation Between Constitutional Skin Color and Photosensitivity Estimated from UV-Induced Erythema and Pigmentation Dose-Response Curves

Cited by 118 publications

References 7 publications

Comparison of Narrow-Band Reflectance Spectrophotometric and Tristimulus Colorimetric Measurements of Skin Color

Comparison of Narrow-Band Reflectance Spectrophotometric and Tristimulus Colorimetric Measurements of Skin Color

Measurement of Color Parameters of Psoriatic Plaques by Narrow-Band Reflectance Spectrophotometry and Tristimulus Colorimetry

Topical Metronidazole Does Not Abate UVB-Induced Erythema

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