The recurrent basal cell epithelioma. A study of 100 cases of recurrent, re-treated basal cell epitheliomas

Menn, H.

doi:10.1001/archderm.103.6.628

Cited by 63 publications

(41 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Earlier studies of Bart et al (2) and Menn et al (8) showed that recurrence rates were unrelated to lesion diameter. In a review by Dellon (9), two studies found that a size of greater than 3 cm was related to tumor recurrence, but four studies concluded that no such relationship existed.…”

Section: Tumor Sizementioning

confidence: 86%

“…Recurrent lesions are buried beneath scar tissue, which acts as a barrier to upward migration; thus, a lesion may progress deeply before detection (14). Clinical borders often are more difficult to estimate (8). Furthermore, recurrent tumors tend to adopt a more aggressive histology than seen in the original tumor (8), and perineural invasion is most common in recurrent tumors (16).…”

Section: Recurrent Tumorsmentioning

confidence: 99%

“…Clinical borders often are more difficult to estimate (8). Furthermore, recurrent tumors tend to adopt a more aggressive histology than seen in the original tumor (8), and perineural invasion is most common in recurrent tumors (16). For these reasons, treatment is difficult.…”

Section: Recurrent Tumorsmentioning

confidence: 99%

“…For these reasons, treatment is difficult. Menn et al (8) reported that basal cell carcinomas that recur after any of the three conventional methods of treatment (excisional surgery, radiation therapy, curettage and desiccation) have a higher rate of second recurrence--49.2%, whether the second treatment is the same or different. Sixty percent of tumors that were treated with curettage and desiccation a second time recurred.…”

Section: Recurrent Tumorsmentioning

confidence: 99%

See 3 more Smart Citations

Difficult Skin Cancers: Clinicopathologic Features and Management

Brown¹

1993

Baylor University Medical Center Proceedings

View full text Add to dashboard Cite

Section: Tumor Sizementioning

confidence: 86%

Section: Recurrent Tumorsmentioning

confidence: 99%

Section: Recurrent Tumorsmentioning

confidence: 99%

Section: Recurrent Tumorsmentioning

confidence: 99%

See 2 more Smart Citations

Difficult Skin Cancers: Clinicopathologic Features and Management

Brown¹

1993

Baylor University Medical Center Proceedings

View full text Add to dashboard Cite

“…According to the literature, surgically excised primary BCCs may show a recurrence rate that varies from 5 to 14% (7)(8)(9)(10)(11)(12). The rates of recurrence appear to depend, to a large extent, on the anatomical localization, the histological characteristics, the initial treatment strategy and the eventual neoplastic margin involvement.…”

Section: Introductionmentioning

confidence: 99%

Facial basal cell carcinoma: Analysis of recurrence and follow-up strategies

Sartore

Lancerotto²,

Salmaso³

et al. 2011

Oncol Rep

View full text Add to dashboard Cite

Abstract. Rates of recurrence after incomplete surgical excision of basal cell carcinoma (BCC) range from 4 to 16.6% of analyzed cases. The aim of the present study was to identify the predictive factors associated with facial BBC recurrence following excision and their influences, in order to establish a proper therapeutic strategy. A monocentric retrospective study was performed reviewing all BCCs surgically excised at the Institute of Plastic Surgery, University of Padua, with particular focus on the involvement of surgical margins and recurrence. Seven hundred and nineteen lesions in 605 patients were studied. Correlations between recurrence probability and various characteristics of BCC were analyzed using a logistic regression model. It was observed that incomplete excision, deep margin involvement, the presence of sclerodermiform or metatypic basaloid squamous cells, as well as pleomorphous histological variants and/or peritumoral inflammatory infiltrates, were all related to an increase in the probability of recurrence. BCC excision must be followed by individualized management with particular consideration for the localization, the histological type and other known predisposing factors; the treatment strategy and, in particular, the length of the surveillance period and the frequency of patient assessment should be evaluated on the basis of the recurrence probability outlined.

show abstract

Predictors of Extensive Subclinical Spread in Nonmelanoma Skin Cancer Treated With Mohs Micrographic Surgery

Batra¹

2002

Arch Dermatol

155

130

View full text Add to dashboard Cite

Background: In nonmelanoma skin cancer, the clinically visible portion may represent a small fraction of microscopic tumor spread. Previous studies have examined individual risk factors for subclinical spread based on patient and tumor characteristics. However, these risk factors have not been prioritized or studied in combination.Objective: To identify the most predictive risk factors for extensive subclinical tumor spread.Design: Retrospective analysis of 1131 Mohs micrographic surgical cases. Variables analyzed included patient age, sex, and immune status and lesion size, location, histologic subtype, and recurrence. Logistic regression was applied to identify important combinations of tumor characteristics and to quantify relative odds of spread.Setting: Academic referral center.Patients: Consecutive sample of all referred patients treated by a single Mohs micrographic surgeon in a 3-year period.Main Outcome Measure: Number of Mohs micrographic surgical layers required to clear a tumor, with 3 or more layers defined as extensive subclinical spread.Results: The highest-risk tumors, with odds ratios greater than 6.0, were basosquamous and morpheaform basal cell carcinoma (BCC) on the nose, morpheaform BCC on the cheek, and those with a preoperative size greater than 25 mm. Other important risk factors were recurrent and nodular BCC on the nose; location on the eyelid, temple, or ear helix; neck tumors and recurrent BCC in men; and tumor size greater than 10 mm. Patients younger than 35 years were at lower risk. Increasing age and immunocompromise were not significant predictors. Conclusion:Identification of lesions likely to exhibit extensive subclinical spread can help guide management to ensure complete tumor eradication and thereby reduce the risk of recurrence and its associated morbidity and cost.

show abstract

The recurrent basal cell epithelioma. A study of 100 cases of recurrent, re-treated basal cell epitheliomas

Cited by 63 publications

References 0 publications

Difficult Skin Cancers: Clinicopathologic Features and Management

Difficult Skin Cancers: Clinicopathologic Features and Management

Facial basal cell carcinoma: Analysis of recurrence and follow-up strategies

Predictors of Extensive Subclinical Spread in Nonmelanoma Skin Cancer Treated With Mohs Micrographic Surgery

Contact Info

Product

Resources

About