The recognition and management of albinism

Abadi, Richard V.; Pascal, Eve

doi:10.1111/j.1475-1313.1989.tb00797.x

Cited by 53 publications

(22 citation statements)

References 59 publications

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“…OCA people have reduced melanin in the eyes, skin and hair, whereas OA involves reduced or absent melanin only in the eyes. 5 OCA is further categorized as incomplete OCA (reduced melanin) or complete OCA (absent melanin). OCA affects an estimated one in 17,000 people in Nepal.…”

Section: 4mentioning

confidence: 99%

Effectiveness of refractive error correction for people with oculocutaneous albinism in Nepal

et al. 2017

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Background: Albinism is commonly associated with high refractive errors, but some clinicians are reluctant to prescribe glasses because reduced vision persists due to additional non-refractive visual problems.Aims and Objective: The purpose of this study was to evaluate the effectiveness of glasses in people with oculocutaneous albinism in Nepal.Materials and Methods: People with Oculocutaneous albinism (OCA) were prospectively examined through an outreach program of Lumbini Eye Institute, Nepal. Glasses were prescribed to determine the objective improvement in visual acuity (VA) and strabismus. Compliance with spectacles wear was assessed by telephone contact after 3 weeks and categorized as excellent: >75% of awake hours; good: 50–75% of awake hours; fair: 26–50% of awake hours and poor: <25%.Results: Thirty one people (65% male) mean age 18 years (range: 3 to 50) with OCA were examined. Mean refractive correction was –0.40±4.3 diopters spherical equivalents (range: −11.0 to +7.0 D). Mean visual acuity at distance was 0.9±0.28(6/50) corrected and 1.150.31(5/60) uncorrected (P = 0.000) in 62 eyes. Mean neat VA was1.74±0.89M corrected and 2.06±1.20M uncorrected (P = 0.004). Forty eight per cent (15 people) had fusion with or without glasses and one had fusion only with glasses. Compliance was excellent in 52% (16), fair in 26% (8), good in 12% (4), and poor in 10% (3).Conclusion: Providing eye glasses resulted in a clinically and functionally significant improvement in visual acuity and function in people with OCA.Asian Journal of Medical Sciences Vol.8(6) 2017 30-34

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Section: 4mentioning

confidence: 99%

Effectiveness of refractive error correction for people with oculocutaneous albinism in Nepal

et al. 2017

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“…In some cases albinism or similar pigmentation disorders have been shown to be caused by autosomal dominant or sex-linked alleles [e.g., Hutt and Mueller, 1942;Pipkin and Bedichek Pipkin, 1942]. Albinism is frequently associated with other defects such as abnormal optical nerve tracts resulting in visual defects [Witkop, 1975;Witkop et al, 1983;Guillery, 1986;Abadi and Pascal, 1989].…”

Section: Mode Of Inheritancementioning

confidence: 98%

Hereditary defects and conservation genetic management of captive populations

Laikre

1999

Zoo Biol.

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“…Acuities typically range from 20/80 to 20/400. Ophthalmic signs include nystagmus, foveal hypoplasia, iris transillumination defects, and reduced stereopsis [1,2]. Low vision rehabilitation (LVR) care is an on-going treatment that evolves as the needs of the patient grow.…”

Section: Introductionmentioning

confidence: 99%