The Reaction of PuIV with the Iron Transport System in Human Blood Serum

Lymph transport of ²³⁹PuO₂ in dogs

“…These results, which are similar to those seen for Pu binding by plasma proteins (Boocock and Popplewell, 1965;Popplewell and Boocock, 1967;Stevens etal·, 1968;Stover et al·, 1968;Turner and Taylor, 1968), were not unexpected, since the protein composition of lymph is qualitatively identical to the protein composition of plasma.…”

“…Since Pu in blood plasma has been shown to be protein-bound (Boocock and Popplewell, 1965;Popplewell and Boocock, 1967;Stevens .et.al·, 1968;Stover et al·, 1968;Turner and Taylor, 1968),the Pu present in the acellular lymph fraction, which is qualitatively identical with plasma, was assumed to be protein-bound. Therefore, disc electrophoresis, a technique capable of separating proteins, was used to determine whether or not the Pu carried in lymph was protein-bound.…”

Relative Distribution of Plutonium and Americium Following Experimental PuO2 Implants

“…These bones have high blood circulation and high blood cell forming activity. Soluble plutonium and americium transport in the body has been reported to be primarily by the blood protein, transferrin (28) and deposition of dissolved Pu and Am at sites of red blood cell formation would not be unexpected. The proximal end of the femur was the only skeletal tissue showing a significant DTPA treatment effect at the 5 % error level.…”

Translocation dynamics of 239-plutonium

“…Pu:in the cells of the alveolar wall may account for the prolonged retention of the ·nuclide inthe lung (Taylor, 1972 Am from the body by tr.eatment with chelating agents (Taylor, 1962 (Stevens, Bruenger, and·Stover, 1965 (Stevens, Bruenger, and:Stover, 1968 (Taylor, 1969). Johnson (1969) also suggested that these two .mechanisms of translocation are important pathways in the systemic deposition of subcutaneously·placed Pu02 nnaterial.…”