The Radiologic Characteristics and Retinal Thickness Are Correlated With Visual Field Defect in Patients With a Pituitary Mass

Suh, H.; Choi, Hoo‐Kyun; Jeon, Hyeshin

doi:10.1097/wno.0000000000001011

Cited by 6 publications

(7 citation statements)

References 20 publications

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“…As demonstrated in several previous studies, visual functional data and structural data including both retinal thickness and tumor biometrics show strong correlations in chiasmal compressing disorder. 16,21 However, visual recovery and structural data showed contradictory results in the current study. Two anatomical structures showed different efficacies in estimating the postoperative VFD restoration.…”

Section: Discussioncontrasting

confidence: 73%

“…6,18–20 Recently, our study group reported that biometrics measured by OCT and MRI reflect VFD well and that these two factors are significantly correlated. 21 However, studies investigating these tumor metrics and visual prognosis have revealed conflicting results. 2,3,22…”

Section: Introductionmentioning

confidence: 99%

“…6,[18][19][20] Recently, our study group reported that biometrics measured by OCT and MRI reflect VFD well and that these two factors are significantly correlated. 21 However, studies investigating these tumor metrics and visual prognosis have revealed conflicting results. 2,3,22 Therefore, in this study, we aimed to investigate the predictive value of retinal thickness and mass biometrics using OCT and MRI, respectively, for restoration of VFD in patients after surgery for removal of a mass compressing the optic chiasm.…”

Section: Introductionmentioning

confidence: 99%

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Predictive value of OCT and MRI for postoperative visual recovery in patients with chiasmal compressive lesions

Jeon

Suh

Kim

et al. 2022

European Journal of Ophthalmology

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Purpose We aimed to investigate the predictive value of retinal thickness measured by optical coherence tomography (OCT) and mass biometrics measured using magnetic resonance image (MRI) for visual recovery after surgery for removal of a mass compressing the optic chiasm. Methods Consecutive patients who showed typical temporal visual field defect (VFD) with respect to the vertical meridian due to a chiasmal compressive mass and who underwent mass removal surgery were recruited. Ophthalmic examination was performed preoperatively and postoperatively. Retinal thickness was measured by the Cirrus OCT. The height and size of the mass and suprasellar extension (SSE) in both the sagittal and coronal planes were evaluated. Patients were divided into two groups based on the improvement in VFD (mean deviation [MD] change ≥ 5 dB: group R; others: group NR) and clinical characteristics were compared. Results Fifteen patients were included in the study. Eight (53.3%) patients were allocated into group R and others (7 patients, 46.7%) into group NR. Age, sex, initial visual acuity, initial MD was not different between the two groups. The retinal thicknesses were not different while tumor height, volume, and both sagittal and coronal SSE were significantly different between the two groups. (p = 0.029, 0.014, <0.001, and <0.001, respectively) All MRI parameters showed significant predictive value for the degree of MD recovery. Conclusion MRI showed better predictive value than OCT in predicting postoperative VFD recovery in patients with temporal VFDs due to chiasmal compressive disorder.

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Section: Discussioncontrasting

confidence: 73%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Predictive value of OCT and MRI for postoperative visual recovery in patients with chiasmal compressive lesions

Jeon

Suh

Kim

et al. 2022

European Journal of Ophthalmology

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“…Because highly myopic patients have a higher diopter accompanied by astigmatism, vitreous opacity and other features, and their fundus lesions are not easily visible under direct test lens, so fundus fluorography is the best method for screening fundus lesions in them [ 17 , 18 ]. Fundus fluorescence imaging can present retinal and choroidal blood circulation, and dynamically and objectively record small changes in the center and periphery of the macula in affected eyes of patients with high myopia, which is beneficial for providing an objective basis for clinical treatment.…”

Section: Discussionmentioning

confidence: 99%

Value of Combining Optical Coherence Tomography with Fundus Photography in Screening Retinopathy in Patients with High Myopia

Hao

Liu

2022

Journal of Healthcare Engineering

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Objective. To explore the value of combining optical coherence tomography (OCT) with fundus photography in screening retinopathy in patients with high myopia. Methods. By means of retrospective study, 40 high myopia patients with retinopathy treated in our hospital from January 2020 to January 2021 were selected as the study group, and 40 healthy individuals in the same period were included in the control group. All patients received traditional ophthalmic examination, and accepted fundus fluorescence imaging, OCT, and fundus photography examination step by step by the same operator. After that, three physicians read the slides by the double blind method, and took the results of fundus fluorescence imaging as the gold standard to analyze the diagnostic efficacy of OCT, fundus photography and their combination. Results. The clinical data and examination results showed that no statistical differences in general data including patients’ mean age, gender ratio, and educational degree between the study group and the control group were observed (P > 0.05), and the nerve thickness above/below the optic disk and temporal/nasal nerve thickness of the optic disk of the study group were significantly different from those of the control group (P < 0.001); the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy rate of diagnosis of combining OCT with fundus photography were respectively 95.0%, 97.5%, 97.4%, 95.1%, and 96.3%, which were significantly higher than OCT or fundus photography alone (P < 0.05); and for combined examination, AUC (95%CI) = 0.963 (0.000–1.000). Conclusion. Combining OCT with fundus photography can effectively identify high myopia patients with retinopathy, which is conducive to improving clinical positive ratio and providing objective basis for treatment.

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“…Binasal thinning of the GCC has been reported to precede bitemporal VF defects in patients with chiasmal lesions (17–19). The nasal GCC is normally thicker than the temporal side in healthy subjects, and loss of this asymmetry is also indicative of chiasm compression (18).…”

Section: Discussionmentioning

confidence: 99%

Junctional Scotoma and Patterns of Visual Field Defects Produced by Lesions Involving the Optic Chiasm

Donaldson¹,

Eshtiaghi²,

Sacco³

et al. 2021

Journal of Neuro-Ophthalmology

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Background: Lesions of the optic chiasm (OC) typically produce bitemporal hemianopia (BTH) on visual field (VF) testing, whereas lesions located at the nasal optic nervechiasmal (ON-OC) junction have been proposed to produce junctional scotoma (JXS), a central defect in the ipsilateral eye with temporal field loss in the contralateral eye. In this study, we investigated whether the pattern of VF loss in patients with chiasmal compression predicted the appearance of the causative lesion on neuroimaging and described the clinical presentation of these patients with different types of VF defect. Methods: Retrospective chart review of patients seen in tertiary neuro-ophthalmology practice over 6 consecutive years with lesions abutting or displacing the OC was performed. Lesion size and location relative to the OC on neuroimaging was determined and correlated with VF defects as well as optical coherence tomography (OCT) of the peripapillary retinal nerve fiber layer and macular ganglion cell complex (GCC). Results: Fifty-three patients were enrolled. VFs demonstrated JXS (n = 18), BTH (n = 14), monocular VF defect (n = 4), and no VF defect (n = 17); 64.7% of cases with normal VFs had radiologic OC compression. Lesion volume was highest in the JXS group, and these patients also had the poorest presenting visual acuity. All patients with JXS showed involvement of the ON-OC junction; however, not all cases showed compression of the OC from the nasal direction (15 of 18), and 17 of 18 also showed compression of one or both prechiasmatic ONs. Compression of the ON-OC junction was also seen in 79% of BTH, 100% of monocular VF defect, and 59% of no VF defect cases. Fifty percent of patients with normal VFs already had thinning of the GCC on OCT. GCC thinning was most pronounced nasally in the BTH group, but diffuse bilateral thinning was found in 38% of cases compared with 60% of JXS. VFs improved in 6 of 6 patients with BTH but only in 5 of 8 JXS cases after treatment. Conclusions: JXS is more often seen with larger lesions and when there is compression of both the prechiasmatic ON and ON-OC junction. These patients have worse presenting visual acuity and poorer outcomes. Not all patients with radiologic compression had VF defects, although 50% of patients with normal VFs had evidence of compression on the macular GCC analysis, emphasizing the importance of macular OCT in the evaluation of patients with lesions involving the OC.

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The Radiologic Characteristics and Retinal Thickness Are Correlated With Visual Field Defect in Patients With a Pituitary Mass

Cited by 6 publications

References 20 publications

Predictive value of OCT and MRI for postoperative visual recovery in patients with chiasmal compressive lesions

Predictive value of OCT and MRI for postoperative visual recovery in patients with chiasmal compressive lesions

Value of Combining Optical Coherence Tomography with Fundus Photography in Screening Retinopathy in Patients with High Myopia

Junctional Scotoma and Patterns of Visual Field Defects Produced by Lesions Involving the Optic Chiasm

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