The radial artery for coronary artery bypass grafting: Clinical and angiographic results at five years

Acar, Christophe; Ramsheyi, Amhad; Pagny, Jean-Yves; Jebara, Victor A.; Barrier, Pascal; Fabiani, Jean‐Noël; Guermonprez, J L; Carpentier, Alain

doi:10.1016/s0022-5223(98)70050-9

Cited by 339 publications

(202 citation statements)

References 16 publications

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“…15 Superficially, these reports contradict the present findings; however, these and other long-term angiographic studies largely consisted of patients without symptoms or evidence of myocardial ischemia. 11,12,14,15 Among the 14 symptomatic patients in the first study and 15 patients in the second study, the patency rates were considerably lower: 64% and 73%, respectively. In addition, a recent larger study of 109 patients who underwent cardiac catheterization for symptoms of ischemia showed an overall patency rate of the radial artery graft of only 75.1% at a mean follow-up of 2.3 years.…”

Section: Discussionmentioning

confidence: 85%

Radial Artery Bypass Grafts Have an Increased Occurrence of Angiographically Severe Stenosis and Occlusion Compared With Left Internal Mammary Arteries and Saphenous Vein Grafts

et al. 2004

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Section: Discussionmentioning

confidence: 85%

Radial Artery Bypass Grafts Have an Increased Occurrence of Angiographically Severe Stenosis and Occlusion Compared With Left Internal Mammary Arteries and Saphenous Vein Grafts

et al. 2004

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“…3,4 The radial artery has recently been rejuvenated as a bypass conduit with encouraging early and intermediate-term results. Some of this success has been attributed to improved harvesting techniques and prolonged administration of antispasmodic agents, [12][13][14] in keeping with the tendency of the radial artery for vasospasm. 15,16 However, ⅐NO-mediated relaxation of the radial artery compared with internal mammary artery and saphenous vein is not yet defined.…”

mentioning

confidence: 99%

Enhanced Nitric Oxide-Mediated Vascular Relaxation in Radial Artery Compared With Internal Mammary Artery or Saphenous Vein

Shapira

Xu²,

Aldea³

et al. 1999

Circulation

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Background-The superior long-term patency of internal mammary artery coronary bypass grafts compared with venous grafts has been attributed in part to increased endothelium-derived nitric oxide (⅐NO) production. Interest in the radial artery as an alternative bypass conduit has recently been revived; however, its biological characteristics remain incompletely defined. The purpose of this study was to compare the ⅐NO-mediated vasomotor properties of the radial artery to those of the internal mammary artery and saphenous vein. Methods and Results-Matched segments of radial artery, internal mammary artery, and saphenous vein (nϭ24 patients)were examined by use of organ-chamber methodology. Endothelium-dependent and -independent vasomotor responses were assessed by dose-response curves to acetylcholine, N G -nitro-L-arginine methyl ester (L-NAME), 8-bromo-cyclic 3Ј,5Ј-guanosine monophosphate (8-bromo-cGMP), and nitroglycerin. Maximum ⅐NO-mediated radial artery relaxation in response to acetylcholine (86Ϯ10%) was significantly greater than internal mammary artery (56Ϯ9%) or saphenous vein (11Ϯ5%, both PϽ0.0001). Similarly, acetylcholine-stimulated cGMP accumulation in radial artery (9.1Ϯ1.7 pmol/mg protein) was also greater than internal mammary artery (6.2Ϯ0.3 pmol/mg protein) or saphenous vein (1.4Ϯ0.2 pmol/mg protein, both PϽ0.05). Estimated basal endothelial ⅐NO production, assayed as the percent maximum contraction in response to L-NAME, was greater in radial artery (39Ϯ5%) than internal mammary artery (23Ϯ6%) or saphenous vein (5Ϯ2%, both PϽ0.05). Maximum relaxation of all vessels to nitroglycerin was similar, although the sensitivity of radial artery to nitroglycerin was greater (EC 50 ϭ33Ϯ7 nmol/L) than the internal mammary artery (203Ϯ32 nmol/L) or saphenous vein (97Ϯ12 nmol/L, both PϽ0.05). Vascular cGMP in response to 0.1 mol/L nitroglycerin was significantly higher in the radial artery (8.3Ϯ1.4 pmol/mg protein) compared with the internal mammary artery (3.5Ϯ1.3 pmol/mg protein) or saphenous vein (1.4Ϯ0.3 pmol/mg protein, both PϽ0.0001). Relaxation to 8-bromo-cGMP was identical for all 3 conduits. Conclusions-These data indicate that ⅐NO-dependent relaxation of radial artery is greater than that of internal mammary artery or saphenous vein. This difference is related to endothelial production of ⅐NO and/or vessel sensitivity to ⅐NO.

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“…The patency rate at five years post-grafting of RA is between 83% to 91% 4 , and the exact mechanism for these high rates of graft failure is unknown. Many hypotheses have been proposed to explain the presence of stenosis in grafts of RA: vasospasm, competitive flow from native circulation, neointimal hyperplasia, endothelial lesion during manipulation of the graft or technical problems during surgery 5 .…”

Section: Discussionmentioning

confidence: 99%

Dificuldade técnica no implante de stent Supralimus em enxerto de artéria radial

Meireles¹,

Kreimer²,

Galon³

et al. 2011

Arq. Bras. Cardiol.

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The radial artery for coronary artery bypass grafting: Clinical and angiographic results at five years

Abstract: The use of the radial artery for coronary bypass grafting provides excellent clinical and angiographic results at 5 years. Routine use of the radial artery in combination with the left internal thoracic artery can be recommended.

Cited by 339 publications

References 16 publications

Radial Artery Bypass Grafts Have an Increased Occurrence of Angiographically Severe Stenosis and Occlusion Compared With Left Internal Mammary Arteries and Saphenous Vein Grafts

Radial Artery Bypass Grafts Have an Increased Occurrence of Angiographically Severe Stenosis and Occlusion Compared With Left Internal Mammary Arteries and Saphenous Vein Grafts

Enhanced Nitric Oxide-Mediated Vascular Relaxation in Radial Artery Compared With Internal Mammary Artery or Saphenous Vein

Dificuldade técnica no implante de stent Supralimus em enxerto de artéria radial

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