The pyrethrins and related compounds. Part XXVI. Analogues of fenvalerate from acyclic‐substituted 3‐methylbutyric and related acids

Abstract

3-Methylbutyric and 3-methylbut-3-enoic acids were prepared and esterified with pyrethroidal alcohols. The insecticidal activities of 46 esters, analogues of fenvalerate in which non-aryl substituents replaced the 4-chlorophenyl group, were determined to establish the structural requirements for activity in this part of the molecule.a Part XXV was published in Pestic. Sci. 1981, 12, 503-508.

Synthesis and some larvicidal properties of 2,3-secopermethrin

“…Although cleavage of the 2,3-position in permethrin is detrimental to activity, the activity was not abolished as was the case for the monosubstituted ester (8). This study reinforces the idea (Elliott et al, 1983) that two «-substituents are important structural features for insecticidal activity in acyclic analogues of pyrethroid acids.…”

“…Research Station, Agriculture Canada, Lethbridge, Alberta, Canada TU 4B1. comparisons of insecticidal properties to permethrin and fenvalerate have not been made. A variety of related acyclic esters have recently been synthesized and tested (Elliott et al, 1983).…”