2012
DOI: 10.1016/j.etap.2012.03.009
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The protective role of vitamin E on gill and liver tissue histopathology and micronucleus frequencies in peripheral erythrocytes of Oreochromis niloticus exposed to deltamethrin

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Cited by 41 publications
(16 citation statements)
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“…Vitamin E is a group of fatsoluble compounds, including d-alpha-tocopherol, which has strong antioxidant activity [44]. Our result is consistent with previous studies that demonstrated the protective effects of vitamin E against the genotoxicity of several agents such as deltamethrin and patulin [45,46]. Thus, vitamin E has the potential to be used as a protective drug against the genotoxicity associated with mutagenic agents and diseases.…”
Section: Discussionsupporting
confidence: 93%
“…Vitamin E is a group of fatsoluble compounds, including d-alpha-tocopherol, which has strong antioxidant activity [44]. Our result is consistent with previous studies that demonstrated the protective effects of vitamin E against the genotoxicity of several agents such as deltamethrin and patulin [45,46]. Thus, vitamin E has the potential to be used as a protective drug against the genotoxicity associated with mutagenic agents and diseases.…”
Section: Discussionsupporting
confidence: 93%
“…Exposure of zebrafish embryos to pyrethroids caused a dose-dependent increase in mortality and pericardial edema, with Type II compounds being the most potent and as doses approaching the LC50, permethrin and deltamethrin caused craniofacial abnormalities (DeMicco et al 2010). The study by Kan et al (2012) suggested deltamethrin to be the causative agents for creating micronucleus and altering the histopathology of liver and gills of Oreochromis niloticus.…”
Section: Histopathological Alterationsmentioning
confidence: 94%
“…Kan et al () observed that vitamin E decreased the histopathological changes induced in gills and liver of O. niloticus by deltamethrin exposure for 30 days, but it did not confer a complete protection. Mekkawy et al () noticed that gills of Cd‐exposed tilapia exhibited severs hyperplasia, proliferation of chloride cells, shortened length and reduced secondary gill lamellae.…”
Section: Discussionmentioning
confidence: 99%